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《Radiologic Practice》 2006-12
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MRI Diagnosis of Spinal Lymphoma and Assessment of Therapeutic Effects

DU Long-tin,ZHU Xiang-ming,LI Jun,et al.MR Section,Xiangfan Central Hospital,Hubei 441021,P.R.China  
Objective:To study MRI manifestation of spinal lymphoma and evaluation of the therapeutic effect.Methods:The MR findings and clinical data in 13 patients with pathologically-proved spinal lymphoma were retrospectively analyzed.Results:Of all 13 patients,5 cases were primary NHL and 8 cases were secondary (7 NHL and 1 HD).Vertebral destruction was found in 11 cases (8 cases involved multiple vertebral and 3 cases involved solitary vertebral),they presented diffuse and patchy long T_1 and long T_2 signal.Mass in the extradural area was found in 9 cases and appeared iso-intense on T_1WI and iso- or hyper-intense on T_2WI,and showed moderate or intense homogenous enhancement.Paravertebral masses were found in 7 cases.Of 7 cases with follow-up,4 cases with primary NHL were re-examined many times in 3~24 months,vertebral and paravertebral lesions were improved,and intraspinal lesions were not found in 3 cases,1 case had no improvement.In one case of lymphoma secondary form meningeal T-cell lymphoma,there was recurrence after eight months after surgery;vertebral and paravertebral lesions recurred in 2 cases with mediastinum and abdomen B-cell NHL in 6~12 months.Conclusion:MRI can clearly display lesions of spinal lymphoma,and can give a correct diagnosis in typical cases,but it should be combined with clinical history in untypical cases.The primary spinal lymphomas after operation and radiotherapy have a better therapeutic effect,the secondary spinal lymphomas recur easily.[
【CateGory Index】: R738.1
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