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《Radiologic Practice》 2007-11
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Role of Clinical Application of Dynamic MR Perfusion Imaging in the Diagnosis of Meningiomas

SUN Yi-li,LI Yang-bin,TAN li-lian,et al.Department of Radiology,the Second Hospital of Guangzhou Medical College,Guangzhou 510260,P.R.China  
Objective:To study the diagnostic and differential diagnostic values of dynamic MR perfusion imaging(DPMRI) in various types of pathologically confirmed meningiomas.Methods:The stuffs of DPMRI of 30 cases of surgically and pathologically confirmed meningiomas,including angiomatous type(n=4),epithelial type(n=11),fibrous type(n=10) and mixed type(n=5),were retrospectively analyzed.The features of MR perfusion curves and artificial color images of the meningiomas were studied and the relative regional cerebral blood volume(rCBV),the mean transit time(MTT) and the rates of maximal descending and ascending slopes of the time/signal intensity curves(MSD) of the tumor parenchyma were measured and statistically treated.Results:The time/signal intensity curves in all types of meningiomas showed negative enhancements.Their ascending and descending portions were asymmetrical and the level of the postcontrast baseline was elevated slowly in contrast to the precontrast one.The descending portion of the perfusion curves of the angiomatous type meningiomas sloped down most abruptly with those of the fibrous and mixed types sloping down less abruptly.That of the fibrous type meningiomas showed a slowly ascending and rather flat curve.The perfusion curves of the epithelial,fibrous and mixed types of meningiomas revealed a small redescending wave before the recovery of original signal intensity.The differences of rCBV and MSD values in various types of meningiomas showed remarkable significance(P0.05),however,the differences in values of MTT and MSI demonstrated no remarkable significance(P0.05).Conclusion:In DPMRI,the measurements and study of the rCBV and MSD values of meningiomas would have been helpful and valuable in the diagnosis and differential diagnosis for various pathological types of meningiomas.
【CateGory Index】: R739.45
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