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《Radiologic Practice》 2010-08
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Preliminary study of computational stability about quantitative DCE-MRI in breast neoplasm

MAO Jian,LI Rui-ming,GU Ya-jia,et al.Department of Radiology,the Affiliated Cancer Hospital of Fudan University,Shanghai 200032,P.R.China  
Objective:To discuss the impact about calculating accuracy of volume transfer constant (Ktrans)in different scan schedules of quantitating breast dynamic contrast enhanced magnetic resonance imaging.Methods:41 patients with breast neoplasms were divided to two groups (A、B) according to examining time.In group A (16 patients) vein remaining needle was inserted and connected to high pressure injector after T1map scan sequence,then automatic prescanning was carried out to determine central frequency of T1 dynamic contrast enhanced scan and dynamic contrast enhanced scan sequence was performed while contrast media was injected.In group B (25 cases ) vein remaining needle was inserted and connected to high pressure injector before T1map scan sequence,automatic prescanning was skipped after T1map scan sequence,then dynamic contrast enhanced scan sequence was carried out and contrast media was injected after first phase scan.Images transferred to GE ADW4.3 workstation and used cine software to calculate Ktrans of neoplasms.In the end,evaluate matching degrees of Ktrans of neoplasms with pathologic result using different scan schedules.Results:T1 maps of group A (16 cases) were obvious mismatch with T1 perfusion maps and Ktrans value of 1 case was compatible with pathologic result,incompatible in 15 cases.T1 maps of group B (25 cases) were match well with T1 perfusion maps and Ktrans value of 24 cases were compatible with pathologic result,incompatible in 1 case.A significant difference was found between those two groups (χ2=29.556,P0.01).Conclusion:Correct planning of scan program and suitable using of parameter in scanning sequence were important for acquiring of accurate angiogenesis parameters.Time selecting of intravenous injection and controlling of central frequency influenced accuracy of Ktrans value directly.
【CateGory Index】: R445.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LANG Ning,XIE Jing-xia Peking University Third Hospital,Beijing 100083 P.R.China;Advances in MRI techniques of breast carcinoma[J];Journal of Medical Imaging;2008-06
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 JI Dong,LI Ming,ZHAO Ze-hua,RUI Yuan-peng,MA Feng-hua Department of Radiology,Putuo Central Hospital,Shanghai Traditional Chinese Medical University 164 Lanxi Rd.,Shanghai 200062,P.R.C.;Correlative Study on MRS,Pathology and Molecular Biology of Breast Cancer[J];Chinese Computed Medical Imaging;2010-02
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 HU Wei Dong,YANG Guo Liang,YUAN Hong Yin,et al.Department of Oncology, the Second Affiliated Hospital of Hubei Medical University, Wuhan 430071,P.R. China;Prognostic significance of microvessel density and the expression of vascular endothelial growth factor in axillary node negative breast cancer[J];CHINESE JOURNAL OF CANCER;1999-05
2 CHEN Qin,ZHANG Hao,HE Zhi-yan,et al.Department of Radiology,Shanghai First People′s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080 P.R.China;Value of Spiral CT in the Diagnosis of Mechanical Intestinal Obstruction[J];Radiologic Practice;2007-01
3 GAO Jie, LIU Zhi-yu, BI Yu-shun, et al (Dept. of Human Anatomy, School of Medicine, Shandong University);Expression of vascular endothelial growth factor C mRNA in human breast cancer cell lines[J];Acta Academiae Medicinae Shandong;2002-03
4 ZHAO Bin*, CAI Shi-feng, GAO Pei-hong, PENG Hong-juan. *Shandong University Medical College, Shandong Medical Imaging Research Institute, Jinan 250021, China;The research on distinguishing benign from malignant breast lesions by diffusion-weighted MR imaging[J];Chinese Journal of Radiology;2005-05
5 Jiang Xiaoshan,Huang Xinfu,Li Jiyou,et al.Departments of Surgery and Pathology,School of Oncology,Beijing Medical University,Beijing 100036.;The correlation between tumor angiogenesis and lymph node metastasis in primary breast carcinoma[J];Chiese Journal of Surgery;1997-10
6 Guo Yong, Wang Fulin, Cai Youquan,Cai Zulong,Gao Yuangui(Department of Radiology, Navy General Hospital, Beijing, 100037);Comparison of Apparent Diffusion Coefficient (ADC) with Histologic Cellularity in Breast Tumors[J];Chinese Journal of Medical Imaging;2002-04
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