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《Chinese Journal of Forensic Medicine》 2010-04
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The expression of CCK in atherosclerotic plaque of coronary artery of autopsy

MA Liqin1,2,LAI Maode1,2,ZHOU Ren1,ZHU Youfa1 1.Research Institute of Pathology and Forensic Medicine of Zhejiang University medical college,Hangzhou 310058,China;2.Forensic Science Identification Center of Zhejiang University,Hangzhou 310058,China  
Objective To reveal the expression of CCK in coronary artery atherosclerotic plaques,and further explore the role of CCK in the formation of coronary atherosclerosis.Methods 100 autopsy specimens of coronary atherosclerosis(35~92 years old male)were divided into atherosclerosis-level I~II and III~IV groups,and normal control group.The immunohistochemical technology was adopted.Results The expression of CCK is positive in atherosclerotic groups compare with the negative in control group(P0.01).But it has no significant differences between I~II and III~IV groups(P0.05).Conclusion There exists an expression of CCK in coronary atherosclerotic plaque,and dosen't change with the degrees of atherosclerotic plaque.
【Fund】: 浙江省教育厅资助项目(Y200804132);; 浙江大学医学部“中央高校基本科研业务费专项资金”青年科研创新专项(2009QNA7015)
【CateGory Index】: D919.8
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