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《Acta Materiae Compositae Sinica》 2007-05
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Calcium phosphate porous ceramic scaffolds reinforced by composite gelatin coating

LIU Bin1,LIN Pinghua1,2,GUO Chao1,SHENG Xiaobo1,CHU Chenglin1,DONG Yinsheng1(1.School of Materials Science and Engineering,Southeast University,Nanjing 211189,China; 2.Department of Materials Science and Engineering,Hehai University,Nanjing 210098,China)  
The calcium phosphate porous ceramic scaffolds with high porosity for the bone tissue engineering were fabricated by the foam impregnation technology,and the composite scaffolds composed of ceramic and gelatin were gained by coating the porous ceramic samples with gelatin solution.It was found that gelatin coatings were formed on the pore walls of porous scaffold samples successfully without destroying their porous characteristic,but these coatings improved the compressive strength and compressive modulus of the samples.The scaffolds,coated with gelatin,were characterized by their nonlinear fractural behavior under compressive loading.Especially,the compressive strength value and the compressive modulus value of porous samples coated with 5% gelatin solution were improved from ~1.04MPa and ~0.105GPa to 5.17MPa and 0.325GPa respectively with the high porosity(82.8%) maintained.The results indicate that the gelatin coatings on the surface of pores reinforce the porous ceramic scaffolds effectively.
【Fund】: 江苏省高新技术研究资助项目(BG2001033);; 日本板梢子公司海外基金资助项目
【CateGory Index】: TB302.4
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