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《Chinese Journal of Analytical Chemistry》 1999-04
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Simultaneous Determination of Magnolol and Honoldol by Micelle-Stabilized Fluorimetry

Bai Xiaohong, Wei Yansheng,Liu Changsong (Department of Chemistry, Shanxi University, Taiyuan 030006)  
When sodium dodecyl sulfate was selected as micellar reagent, and 0.1 mol/L sodium acetate-acetic acid buffer (pH = 4) as acid condition, the fluorescence spectra of magnolol and honokiol are observably not only enchanced but also different. Based on the characteristics, a method for the simultaneous determination of magnolol and honokiol by micelle-stabilized fluorimetry was developed. The change of Magnolol and Honokiol concentration in rabbit plasma was continuously monitored with the method, and the drug-time curves were simultaneously constructed.The linear range (g/mL), detectionlimit (g/mL) and RSD(%) of magnolol and honokiol are: magnolol 2×10-7~6X10-6,2×10-9,2.8;honokiol:4×10-7~6×10-6, 2×10-8,10.8, respectively.
【Fund】: 国家自然科学基金资助课题
【CateGory Index】: O657.3
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