Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Analytical Chemistry》 2006-05
Add to Favorite Get Latest Update

The Distribution of Podophyllotoxin in the Different Parts of Dysosma Versipellis (Hance) M. Cheng by Capillary Zone Electrophoresis

Deng Shuduan, Zhao Xingling, Wang Wei , Huang Qiling, Ding Zhongtao, Cao Qiue 1 (Department of Chemistry, Center for Advanced Studies of Medicinal and Organic Chemistry,Yunnan University, Kunming 65009)  
A simple and sensitive capillary zone electrophoresis (CZE) method for the determination of podophyllotoxin (PPT) has been developed, and the distribution of podophyllotoxin in the different part of Dysosma versipellis (Hance) M. Cheng was studied by the proposed method. The results indicated that podophyllotoxin could be separated availably from the other constituents in the different part of Dysosma versipellis (Hance) M. Cheng in an uncoated fused-silica capillary (57 cm×75 μm i.d. with the effective length of 50 cm) using 25 mmol/L borate with pH 10.8 as running buffer. The linear range for the determination of podophyllotoxin was 1.5-171.0 mg/L with the relative standard deviations (n=8) for the relative migration time and peak area of 1.5% and 0.8%, respectively. The results obtained from the determination of podophyllotoxin in the ethanolic extracts of the roots, stems, leaves and fibrils of Dysosma versipellis (Hance) M. Cheng pointed out that the distribution of podophyllotoxin in the different part of Dysosma versipellis (Hance) M. Cheng was not equal . Podophyllotoxin in the roots was highest, and in the leaves was lowest,
【Fund】: 国家自然科学基金(No.30260014 20465003);; 云南省人才培养基金(No.2004PY01~4);; 云南省高等学校教学、科研带头人资助项目
【CateGory Index】: O658.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Yu Peizhong, Yao Liyun *, Wang Liping * (Department of Chemistry of Natural Drugs, School of Pharmacy, Shanghai Medical University, Shanghai 200032; *Department of Chemistry, School of Basic Medical Sciences, Shanghai Second Medical University,;HPLC DETERMINATION OF PODOPHYLLOTOXIN IN FOUR DYSOSMA PLANTS[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1998-06
2 ZHANG Pei-nan1,LI Zhao-feng2,ZHAO Chang-qi 1* (1.Biology Department, Northwest University,Xi'an 710069,China; 2.Shanxi Medicinal Materials Company,Xi'an 710048,China);PODOPHYLLOTOXIN AND ITS DERIVATIVES[J];Natural Product Research and Development;2004-01
3 Ma Shoudong, Meng Qingli(The Ninetyfirst Hospital of PLA, Shandong Yanzhou 272000);Determination of podophyllotoxin by fluorospectrophotometry method[J];CHINESE JOURNAL OF HOSPITAL PHARMACY;1998-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHENG Jian, CHEN Huan wen, LIU Hong wei, LI Bao hua, ZHANG Han qi, YU Ai min, JIN Qin han * (Changchun R&D Center for Analytical Instruments, Department of Chemistry, Jilin University, Changchun, 130023);Application of UV-Vis Spectrophotometry in Pharmaceuticals Analysis[J];Journal of Analytical Science;2002-02
2 YANG Lei1,TANG Xiaoxi1,ZHAO Chunjian1,MA Chunhui1,ZU Yuangang1,YU Zhijia2 (1 Key Laboratory of Forest Plant Ecology,Ministry of Education,Northeast Forestry University,Harbin 150040, Heilongjiang,China;2 Administration of Liupan Mountain National Natural Reserve,Guyuan 756401,Ningxia,China);Optimization of ultrasonic extraction technology of podophyllotoxin from Sinopodophyllum emodi(Wall.)Ying[J];Chemical Industry and Engineering Progress;2009-02
3 ZHANG Jie1,2,ZHOU Chun-shan2,LIU Shao3,CHEN Hao1,YANG Chao3(1.Department of Pharmacy,Third Xiangya Hospital,Changsha 410013;2.College of Chemistry and Chemical Engieering,Changsha 410083;3.Department of Pharmacy,Xiangya Hospital,Changsha 410008;Central South University,China);Effect of podophyllotoxin on human gastric cancer cell line SGC 7901[J];Journal of Central South University(Medical Sciences);2008-08
4 CHEN Yan1,DE Ji2,LIU Qian-ling1,LIU Yun-hua1,YI Jin-hai1(1.Sichuan Academy of Chinese Medicine Sciences,Chengdu,Sichuan,610041 P.R.China;2.Tibet Medical Hospital of Tibet Autonomous Region,Lasa,Xizang,850000 P.R.China);Identification and determination of podophyllotoxin in Sinopodophyllum fruit[J];West China Journal of Pharmaceutical Sciences;2009-01
5 WEN Pu hong (Department of Chemistry and Chemical Engineering,Baoji College of Arts and Science,Baoji 721007,China);A New Technology for Preparing Podophyllotoxin of High Purity[J];Fine Chemicals;2001-10
6 ZHONG Xian-feng HUANG Gui-dong (Food Bioengineering College of Henan University of Science and Technology, Luoyang,Henan 471003,China);The perspective of the function and compositions of lotus leaf[J];Food & Machinery;2006-04
7 CHEN Li TU zi-liang CHEN Ji-yan FANG Jian-min ZHANG You-lin (Affiliated Taihe Hospital of Yunyang Medical College,Shiyan 442000,China);Determination of Podophllotoxin in Dysosma versipellis by HPLC[J];Lishizhen Medicine and Materia Medica Research;2007-09
8 ZHANG Li-yan,WAN Ming-xiang,HE Shun-zhi,YANG Yu-qin,LI Jian(Pharmaceutical Department,Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China);HPLC determination of podophyllotoxin in Dysosma genus from Guizhou province[J];Chinese Journal of Pharmaceutical Analysis;2009-02
9 WAN Zong-ming, CHEN Hong, CAO Bo, WANG Ying, MOU Hong-jun(Department of Pharmacognosy, Medical College of Chinese Peoples Armed Police Forces, Tianjin 300162, China);Mechanism of Podophyllotoxin rheinate (RH-01) on human osteoma sarcomatosum cells growth[J];Chinese Traditional and Herbal Drugs;2008-01
10 HU Yongfang,JIAO Haisheng,ZHU Xingwu,ZHOU Suqin(Dept of Pharmacy,The Second Affiliated Hospital of Lanzhou Medical College,Lanzhou 730030);Determination of the Contents of Podophyllotoxin and Beclometasone Dipropionate in a Preparation by RP-HPLC[J];China Pharmacy;2002-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zhang Dingcheng, Shao Jianzhang and Li Donglin (Department of Biology, Anhui Normal University, Wuhu 241000);A STUDY ON THE KARYOTYPES OF DYSOSMA VERSIPELLIS AND D. PLEIANTHA ENDEMIC TO CHINA[J];Guihaia;1991-01
2 Wang Liping et al(Department of Chemistry,Shanghai Second Medical University);Study on Amino Acids in Bajiaolian and Its Injection[J];JOURNAL OF HARBIN MEDICAL UNIVERSITY;1994-03
3 HUANG Heng-yu 1 MA Shao-bin 2 LI Li 1(The Biology Department of Jishou University, Jishou 416000) (The Biology Department of Yunnan University, Kunming 650091);THE GENESIS OF MICROSPORE AND THE FORMATION OF MALE GAMETOPHYTE IN DYSOSMA VERSIPELLIS(HANCE)M.CHENG[J];Bulletin of Botanical Research;2001-04
4 HUANG Heng-Yu 1,2 MA Shao-Bin 2(1.The Biology Department of Jishou University, Jishou 416000) (2.The Biology Department of Yunnan University, Kunming 650091);The development of megasporogenesis and the formation of female gametophyte in Dysosma versipellis[J];Bulletin of Botanical Research;2004-03
5 Su Yingjuan, Liu Qihong(Wuhan Institute of Botany, Academia Sinica, Wuhan 430074);STUDIES ON THE LEAF EPIDERMIS OF DYSOSMA IN HUBEI PROVINCE[J];Journal of Wuhan Botanical Research;1992-04
6 Zhuang Ping, Wu Hong(Natural Resource Institute of Sichuan, Chengdu 610015)Wu Jialing(Sichuan School of Chinese Medicine, Emei 614201)Liang Kaihe, Zhou Fengming(Biologic Resource Experiment Station of Mr. Emei, Emei 614203);THE STUDY ON ECOLOGICAL AND BIOLOGIC CHARACTERS OF THE GENUS DYSOSMA IN MOUNTAIN EMEI[J];Journal of Wuhan Botanical Research;1993-01
7 LIAO Mao-Chuan 1,2, WANG You-Wei 2, TU Zhi-Ben 2, XIAO Pei-Gen 3(1. National Laboratory of Drugs and Devices for Family Planning, Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China;2. Wuhan Institute of Botany, The Chin;Study on Constituents of Dysosma tsayuensis Ying[J];Journal of Wuhan Botanical Research;2002-01
8 Su Yingjuan;Liu Qihong(Wuhan Institute of Botany, The Chinese Academy of Sciences Wuhan 430074);A STUDY ON THE PEROXIDASE ISOZYMES OF DYSOSMA FROM HUBEI PROVINCE[J];JOURNAL OF WUHAN BOTANICAL RESEARCH;1994-01
9 Su Yingjuan;Liu Qihong(Wuhan Institute of Botany,The Chinese Academy of Sciences Wuhan 430074)Chen Lianyin(Hubei College of Traditional Chinese Medicine Wuhan 430061);THE ANATOMICAL STUDY ON THREE SPECIES OF DYSOSMA IN HUBEI PROVINCE[J];JOURNAL OF WUHAN BOTANICAL RESEARCH;1994-02
10 Su Yingjuan;Liu Qihong(Wuhan Institue of Botany,The Chinese Academy of Sciences Wuhan 430074);A STUDY ON THE POLLEN MORPHOLOGY OF DYSOSMA FROM HUBEI[J];JOURNAL OF WUHAN BOTANICAL RESEARCH;1994-03
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Dong Xiaoping,Zeng Li(Department of Traditional Chinese Pharmacy,Chengdu College of Traditional Chinese Medicine.Chengdu 610075);ISOLATION,IDENTIFICATION AND QUANTITATION DETERMENATION OF PODOPHYLLOTOXIN FROM DYSOMA GENUS PLANTS GROWING IN SICHUAN[J];Natural Product Research and Development;1994-02
2 Bai Yamin (Gansu Institute for Drug Control,Lanzhou) Xu Jianzhong (Gansu Institute of Materia Medica,Lanzhou);Determination of Podophyllotoxin Content in the Root andd Rhizoma of Podophyllum emodi Wall.by HPLC[J];;1988-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved