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《Chinese Journal of Analytical Chemistry》 2007-10
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Antivirus Effect of Volatile Oil from Senecio Cannabifolius Less. and Its Constituents Analysis

He Zhong-Mei1,Meng Xiang-Ying 1,Bao Yong-Li1,Wu Yin2,Zhu Hong-Yan1,Li Yu-Xin2 1(Institute of Genetic and Cytology,Northeast Normal University,Changchun 130024) 2(Research Center of Agriculture and Medicinal Gene Engineering of Ministry of Education,Changchun 130024)  
Essential oil extracted from Senecio cannabifolius Less.of senecioneae of compositae is found to have significant antivirus effect against Respiratory Syncytial Virus and HerpesSimplex Virus 1 and delay pathogenic action of Parainfluenza Virus,Coxsackie Virus B3,Adeno virus-3 and Influenza Virus of Mouse by using cytopathic effect method.In order to find antivirus components,the constituents of essential oil from Senecio cannabifolius Less.were analysed by techniques of GC-MS.The yield of essential oil is 0.22%(mL/100 g) and the identified relative contents of it is 88.47%.26 compounds have been tentatively identified,including n-Hexadecanoic acid(27.01%),carotol(13.73%),9,12-linoleic acid(9.99%),α-pinene(9.28%),β-pinene(5.58%),in which the terpene compounds account for 47.42%,fatty acid account for 37.61% and else compounds only a 3.44%.The results imply terpene and fatty acid with high content may relate to anti-virus activity of essential oil from Senecio cannabifolius Less.
【Fund】: 国家自然科学基金(Nos.30670220 30472169);; 吉林省科技发展计划基金(No.20060904);; 长春市科技局基金(No.2006318);; 国家科技攻关计划基金(No.2004BA907A15);; 东北师范大学测试基金资助项目
【CateGory Index】: R285;R284
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