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《JOURNAL OF RADIATION RESEARCH AND RADIATION PROCESSING》 2000-02
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EFFECTS ON PROLIFERATION AND CELL CYCLE OF IRRADIATED KG-1 CELLS STIMULTATED BY CM-CSF

GUO Dehuang; DONG Bo; WEN Gengyun; LUO Qingliang; MAO Bingzhi (Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850)  
In order to explore the variety of cell proliferation and cell cycle after exposure to ionizing radiation, the responses of irradiated KG-1 cells of the human myeloid leukemia stimulated by GM-CSF, the most common used cytokine in clinic, were investigated. The results showed that GM-CSF enhance KG-1 cells prolifration, reduce G0/G1 block, increase S phase and G2/M phase. The stimulation effects of the GM-CSF is more effective in irradiated group than in control group.
【CateGory Index】: Q6
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【Secondary References】
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