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《Journal of Fujian College of Traditional Chinese Medicine》 2007-03
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Clinical Study of Protective Effect of Tonifying Kidney and Activating Blood decoction on Osteoarthritic Cartilage

PAN Wei-jun1,LIANG Zu-jian2(1.Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510405,China;2.The Third Affiliated Hospital,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510240,China)  
To observe the protective effect of tonifying kidney and activating blood decoction on the articular cartilage of osteoarthritis.60 patients were divided into two groups in a randomized and single-blind method,group A were received TCM treatment and group B were received celecoxib.The clinical curative effects were evaluated by Womac index,and the serum proteoglycans and type II collagen contents were measured by ELISA.The results showed that the curative effect of group A was better than group B after 6 months(P0.01),there were differences in serum proteoglycans and type II collagen contents before and after treatment(P0.01).Conclusion:Tonifying kidney and activating blood decoction have the protective and promotive effect on osteoarthritic articular cartilage.It is valuable to promote its clinical application.
【CateGory Index】: R274
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