Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Forensic Medicine》 2008-05
Add to Favorite Get Latest Update

Changes of RyR_2 mRNA Expression in Rats Suffering from Acute Myocardial Ischemia

JIE Ya1,ZHU Shao-hua1,JIANG Yan-wei2,ZHANG Lei1,FAN Fan1 (1. Department of Forensic Medicine,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China; 2. Tianjin Institute of Criminal Science and Technology,Tianjin 300193,China)  
Objective To investigate the changes of ryanodine receptor 2(RyR2) mRNA expression in rats suffering from acute myocardial ischemia. Methods SD rats were divided randomly into normal control group,myocardial ischemia group and sudden death group. The models of myocardial ischemia and sudden cardiac death were induced by intraperitoneal injection of hypophysine. The changes of RyR2 mRNA expression in cardiac sarcoplasmic reticulum(SR) of rats suffering from myocardial ischemia were detected by fluorescent RT-PCR technique. Results The levels of RyR2 mRNA in the myocardial ischemia group and sudden death group were significant lower than those in the control group(P0.05). Conclusion Myocardial ischemia may induce down-regulation of cardiac SR RyR2 mRNA expression.
【Fund】: 湖北省自然科学基金资助项目(2007ABA293)
【CateGory Index】: D919
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 Department of Pathology, Anhui Medical University, Hefei 230032,Anhui ZHAO Wen-di, WU Ji-feng;Ideas on experimental teaching of pathology[J];Journal of Anhui Health Vocational & Technical College;2005-06
2 Ge Xuan, Ge Dunjun People Hospital of Dongyang City, Zhejiang Province(322100);Analysis on Clinical Causa Morbi of Lacunar Cerebral Infarction[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-05
3 WANG Qiu-jing 1, LU Wen-wei 1, LU Hang 2, LIU Fen 1, YANG Shi-jie 1,HUA Yu-qiang 3, JI Shu-xia 3 (1. Experimental Center of Functional Sciences, School of Basic Medical Sciences, Jilin University,Changchun 130021,China;2.Department of Teaching Center, College of Chemistry,Jilin University, Changchun 130021,China;3.BaiShan Pharmaceutical LimitedCompany of Tonghua City,Jilin Province,Tonghua 134000,China);Effects of QiDong YiXin on hemodynamics and acute myocardial ischemia in anesthetic dogs[J];Journal of Jilin University of (Medicine Edition);2004-05
4 SHI Hong-yu~* WANG Gui-qin. *Department of Hematology,Shanxi Provincial Children and Women Hospital,030013 Taiyuan,China;CD_4~+ CD_(25)~+ regulatory T cell and tumor immunity[J];Journal of Leukemia & Lymphoma;2007-06
5 WEI YU-zhong, SHI Dong-hong,CAO Jian-min,XU Jian,GAO Da-zhi2,KONG Wei-dong Radiology of department, Traditional Chinese medical hospital of Sihong county, Jiangsu province,Sihong 223900,China; Department of Radiology, Nanjing General Hospital of Nanjing Military Region, Nanjing 210002, China;Clinical application of modifi ed percutaneous femoral artery puncture with Seldinger technique[J];Contemporary Medicine;2009-11
6 YUE Shu-Qiang, DOU Ke-feng, YANG Yan-ling.Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032,China;Prevention of Postoperative Abdominal Adhesions by IL-1β and TNFα Antibody in Mice[J];Journal of Chinese Physician;2003-02
7 ;Abdomenal pain,nausea,and respiratory difficulty(the 51~(st) case)[J];Academic Journal of Second Military Medical University;2009-01
8 Lu Wei,Fan Bo-zhen,Li Huai-fang,et al. (Dept.of Obs.& Gyn.,Tongji Hospital,Tongji University,Shanghai 200065,China);The Study of Influencing Factors of Uterine Leiomyomas[J];Chinese Journal of Medicinal Guide;2008-09
9 Wu Jianxin et al(Department of Physiology, Dali Medical College, Dali 671000);Effect of Xinmailong on Lipid Peroxidation in Experimental Rabbits with Lung Injury[J];JOURNAL OF DALI MEDICAL COLLEGE;1998-03
10 SONG Jin-jun,WANG Shang-zhong,CAO Zhi-qing,LEI Xin-li (The Lushan Sanatarium of PLA,Jiujiang 332000,Jiangxi,China);Clinicopathological analysis of cerebral schistosomiasis[J];Journal of Southeast China National Defence Medical Science;2007-01
China Proceedings of conference Full-text Database 1 Hits
1 WANG Bing PAN Yanshu HUA Qian School of Preclinical Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;Quantitative detection of P-glycoprotein in the rat brain[A];[C];2007
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved