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《GUANGDONG MEDICAL JOURNAL》 1998-05
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Yi Guan Jian Prevent the Formation and Promote Healing of Acute Experimental Gastric Ulcer

Li Lin; Liu Ba; Song Xiangzhi, et al . (Department of Traditional Chinese Medicine, Third Affiliated Hospital, Sun Yat-sen University of Medical Sci-ence, Guangzhou 510630.)  
Objective: To observe the effects of Yi Guan Jian on the formation and healing of gastric ulcer. Methods: The arute experimental gastric ulcer model prepared by injecting orally 1ml the ethanol or 0.2 N NaOH into rats was used. Results: Decoction of Yi Guan Jian was administered orally in the dosage of 6.0, 12. 0 or 24.0g/kg respectively in rats, which prevented remarkably the forming of gastric mucosal damage induced by absolut ethanol or 0.2N NaOH in a dose-dependent manner(P 0.01 or 0.001). The inhibitory rates to injury were 6.8%, 37.5% and 93.9% for absolute ethanol-induced damage respectively; 54. 8%, 68. 6% and 98.9% for 0.2N NaOH - induced one. Decoction of Yi Guan Jian(24.0g/kg/day)ana selbex(3. 0mg/kg/day)was administered orally respectively for 3 days, both of which could accelerate recovery of absolute ethanol- induced damage(P 0.05 or 0.001). Conclusions: Yi Guan Jian can prevent the formation and promote the healing of acute gastric ulcer.
【Fund】: 广东省中医药管理局科研基金!95119
【CateGory Index】: R573.1
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 Liu Haijun, Li Zhaoshen, Xu Guoming(Department of Gastroenterology, Changhai Hospital, Second Military Medical University ' Shanghai, 200433);The preventive and treatment effects of selbex on acute gastric mucosal injury in rats[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1996-03
2 Li Lin et al(Third Affiliated Hospital,Sun Yat-sen University of Med, Sci Guangzhou 510630);EFFECT OF REHMANNIAE(RR)ON GASTRIC ACID SECRETION AND GASTRIC ULCER[J];JOURNAL OF HUNAN COLLEGE OF TRADITIONAL CHINESE MEDICINE;1996-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Li Jun,Zhang Liping,Zhang ZhenlingHenan College of Traditional Chinese Medicine;Recent development of Radix rehmanniae[J];Journal of Henan College of Traditional Chinese Medicine;2005-06
2 Li Lin et al(Third Affiliated Hospital,Sun Yat-sen University of Med, Sci Guangzhou 510630);EFFECT OF REHMANNIAE(RR)ON GASTRIC ACID SECRETION AND GASTRIC ULCER[J];JOURNAL OF HUNAN COLLEGE OF TRADITIONAL CHINESE MEDICINE;1996-02
3 QI Hong-jun 1,HU Man-jing 1,SUN Gui-ju 2 (1.Department of Internal Traditional Chinese Medicine,Zhongda Hospital,Southeast University,Nanjing 210009,China; 2.School of Public Health,Southeast University,Nanjing 210009,China);Protective effect of traditional Chinese medicines on gastric mucosa[J];Journal of Southeast University;2003-02
4 ZHAO Xian xing 1, ZHAO Wen kui 2 1. Duhu health section of Chengxiang town, Xiaoshan, Zhejiang 311200; 2. Jinhua school, Zhejiang medical university, Zhejiang 321000, China;Clinical observations on the treatment of duodenal ulcer by acupoint catgut implantation plus Chinese herbs[J];SHANGHAI JOURNAL OF ACUUNCTURE AND MOXIBUSTION;2000-03
5 HU Li-min,FAN Guan-wei,GAO Xiu-mei,et al(Tianjin University of TCM, Tianjin 300193,China);Comparison of Influence of Natural Borneol and Synthetic Borneol onGastric Mucosal Barrier in Rats[J];Journal of Tianjin College of Traditional Chinese Medicine;2005-03
6 LI Lin 1, WANG Zhu li 2, YE Mei hong 2, LAI Xiao rong 2 (1. Department of Traditional Chinese Medicine, Third Affiliated Hospital, Sun Yat sen University of Medical Sciences, Guangzhou, 510630; 2. Department of Physiology, Sun Yat sen Universi;Capsaicin-sensitive Neuron-mediated Protective Effects of the Dry Radix Rehmanniae on Gastric Mucosa[J];ACADEMIC JOURNAL OF SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES;2000-02
7 JIA Jian-wei,ZHAO Jie,LI Qiu-wei,et al.Tianjin Infectious Disease Specialty Hospital(Tianjin,300192)China;Experimental study on protective effects of fresh Rehmannia juice on intestinal ischemia-reperfusion injury in rats[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;2008-06
8 JIANG Shu-min,ZHANG Lin-lin,XIONG Guo-wei,et alThe Hospital Affiliated to Liaoning University of Traditional Chinese Medicine(Shenyang 110032);The Protective Effect of Ningluohumoyangwei Mixture on Rat with Ethanol-induced Acute Gastric Mucosal Injury[J];Journal of Emergency in Traditional Chinese Medicine;2008-02
9 Chen Yongxiang et al (Flrst Affiliated Hospital, Guiyang College Traditional Chinese Medicine, Guiyang 550001);The Effects in the Prophylactive Treatment Yiguan Jian on Four Experimental Gastric Ulcer[J];Pharmacology and Clinics of Chinese Materia Medica;1990-04
10 Chen Yongxiang, et al (First Affiliated Hospital, Guiyang College TCM, Guiyang 550001);The Effects of Yiguan Jian and Its Modifier on Liver Damage in Mice[J];Pharmacology and Clinics of Chinese Materia Medica;1992-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YANG Xuesong; LI Yinong; YE Simao; DONG Xiuyun(Department of Gastroenterology, The Third Hospital,Beijing Medical University 100083);EXPERIMENTAL STUDY OF CORRELATION OF GASTRIC ULCER HEALING QUALITY WITH RISISTANCE TO REINJURY BY PREDNISONE IN RATS[J];Journal of Beijing Medical University;1996-06
2 PENG Cheng, ZHANG Lei, ZHANG Li, et al Medicine College, Chengdu University of TCM (Chengdu, 610075,China);Experimental Studies to Functional Dyspepsiathe Treaed with Sini Powder[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-01
3 CUI Zhong Min, LI Zhao Shen, ZHAN Xian Bao, XU Guo Ming (Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China);Experimental study on the protective effect of endogenous NO on stress-induced gastric mucosal lesions[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;2000-02
4 SUN Feng-peng1, SONG Yu-gang1, ZHU Xin-sheng2, TANG Shi-neng3, DU Jiang3, QIU Qing-lin3, LIANG Qiao-ming3, ZHAO Tong4 (Departments of 1Gastroenterology, 2Pathology, 3Central Laboratory, Zhujiang Hospital, First Military Medical University, Guangzhou 51028;Establishment of acetic acid-induced rat gastric ulcer model and histological observation of the antral mucosa during ulcer healing[J];Journal of First Military Medical University;2001-08
5 LI Yun-cheng,YUAN De-pei,ZHAO Jing-hua (Hubei College of Traditional Clinese Medicine,Wuhan 445000,China);The Experiment Research of Compound Ulcer Medicament Treating the Gastric Ulcer[J];Journal of Hubei Institute For Nationalities Medical Edition;2005-01
6 Wang Zhuli, Li Lin, Lai Xiaorong, et al. Department of Physiology, Sun Yat-sen University of Medical Sciences, Guangzhou 510089;Effects of extract A or B of the dry radix rehmanniae (DRR) on resisting experimental gastric mucosal ulcers[J];GUANGDONG MEDICAL JOURNAL;1999-04
7 Ye Meihong, Wang Zhuli, Li Lin, et al. Department of Physiology, Sun Yat-sen University of Medical Sciences, Guangzhou 510089;Capsaicin-sensitive neurons mediating protective effect of rehmanniac extract on gastric mucosa[J];GUANGDONG MEDICAL JOURNAL;2000-01
8 Tao Xiuliang Li Guocheng Luo Shuxing (Department of Traditional Chinese Medicine, Tongji Hospital, Tongji Medical Uniersity, Wuhan 430030 China);EFFECT OF XIAO KUI LING PRESCRIPTIION ON THE EXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTOR DURING GASTRIC ULCER HEALING IN RATS[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;1998-04
9 Wang Hesheng; et al(Department of Biochemistry Guiyang College of Traditional Chinese Medicine);Effects of Yiguan Jian and its Polysaccharicles on the Activity of SOD in Red Cells and Tissues of Rats[J];JOURNAL OF GUIYANG MEDICAL COLLEGE;1996-04
10 Deng Changsheng;Huang Meifang;Gao Zhiqing,et al(Department of Medicine,Second Affiliated Hospitial,Hubei Medical University,Wuhan 430070,China);Effect of Radix Salvia Miltiorrhiza on Levels of LPO SOD and GSH-Px in Rats with Acute Gastric Mucosal Damage[J];ACTA ACADEMIAE MEDICINAE HUBEI;1995-02
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 DU Xiu-fang,YANG Zhen,MENG Ling,et al.(Chengdu Medical College,Chengdu 610081,China);THE TREATMENT RESEARCH OF STRESS GASTRIC ULCER[J];Modern Preventive Medicine;2008-19
2 ZHANG Ting,MA Sheng-lin,YUE Jian-hua,et al Center of Tumor,Hangzhou Hospital of Armed Police Forces of Zhejiang Province,Hangzhou(310051);Clinical Study on Toxicity-attenuation Effect of Yiguan Decoction in Treatment of Non-small Cell Lung Cancer with NP Protocol of Chemotherapy[J];Chinese Journal of Integrated Traditional and Western Medicine;2007-05
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Cao Xihua et al.(Section of Pharmacology,Beijing University of TCM,Beijing 100029);Protective Effect of Decoction of Glehnia and Ophiopogon on the Injury of Gastric Mucosa of Rat[J];JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1994-04
2 Ren Guangrng Gong Zhengliang;A Study on the Pathological Factors of the Various Types of Peptic Ulcers and on Their Function of Secreting Gastric Acid[J];;1987-02
3 Chen Yong (Institute of Viscera-Stale and liver Diseases, Hubei College of Traditional Chinese Medicine, Wuhan 430061);EFFECTS OF HEAT-CLEARING HERBS AND YIN-NOURISHING HERBS ON GASTROITESTINAL MOTILITY[J];Pharmacology and Clinics of Chinese Materia Medica;1992-03
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