Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Guangdong Medical Journal》 2001-03
Add to Favorite Get Latest Update

Natural killer cell activity and cytokines levels in peritoneal fluid of patients with endometriosis

Zhou Longshu, Xiao Qing, Huang Liping, et al. Department of Obstetrics and Gynecology, General Hospital of Guangzhou Command of PLA, Guangzhou 510010  
Objective To study the change and significance of natural killer cell (NK cell)activity, interleukin-6(IL-6),interleukin-8(IL-8) and tumor necrosis factor-α(TNF-α) levels in peritoneal fluid of patients with endometriosis. Methods\ 32 patients with endometriosis were divided into two groups(mild group: 13,stageⅠ or Ⅱ; severe group: 19,stage Ⅲ or Ⅳ ). 21 controls were also included. The NK cell activity and levels of IL-6,IL-8 and TNF-α in peritoneal fluid were measured by radioisotope method or enzyme linked immunosorbent assays. Results\ The NK cell activity in peritoneal fluid from two endometriosis groups was significantly lower than that in controls ( P 0 01), and NK cell activity of severe group was significantly lower than that of mild group.The concentrations of IL-6,IL-8 and TNF-α were significantly higher in two endometriosis groups than those in controls ( P 0 01), with significant differences between two endometriosis groups ( P 0.01).Conclusions\ The immune function of peritoneal fluid of patients with endometriosis is impaired. The NK cell activity is lower,the levels of IL-6,IL-8 and TNF-α are higher. The clinical stage of endometriosis is positively correlated to cytokine level and negatively correlated to NK cell activily. They may participate in the pathogenesis of endometriosis.
【CateGory Index】: R711.71
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 WANG Hui min,FENG Su yun (Dept.of Acupuncture & Massage,Zhejiang College of TCM,Hangzhou,Zhejiang 310053,China);Influence of Medicinal Cake-partition Moxibustion on Serum IL-6 in Endometriosis Rats[J];Journal of Fujian College of Traditional Chinese Medicine;2003-04
Chinese Journal Full-text Database 2 Hits
1 HAO Min, SHI Yifu, DONG Minyue. Department of Gynecology, Obstetrics and Gynecology Hospital of Zhejiang Medical College, Zhejiang University, Hangzhou 310006, China;Measurements of Interleukin-6, Interleukin-8 and Transforming Growth Factor-β_1 Levels in Peritoneal Fluid of Patients with Endometriosis[J];Chinese Journal of Obstetrics And Gynecology;2000-06
2 LIU Yi*, LUO Lilan, ZHAO Haibo.* Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical University, Wuhan 430022, China;Changes of Tumor Necrosis Factor Alpha and Interleukin-6 Levels in Peritoneal Fluid of Patients with Endometriosis and Their Effects on Human Sperm Motility and Mouse Embryo Development[J];Chinese Journal of Obstetrics And Gynecology;2000-06
Chinese Journal Full-text Database 10 Hits
1 ZUO Lian-dong 1, ZHENG Hui 1, LI Hong-yi 2 (1.Medical College of Jinan University, Guangzhou 510632, China; 2.Medical College of Zhongshan University, Guangzhou 510089, China);Meta-analysis of Interleukin-6 Concentration in Peritoneal Fluid of Women with Endometriosis[J];Labeled Immunoassays and Clinical Medicine;2003-01
2 CAO Shu -jun, LUO Yi, LIU Yong -zhen, et al.(Taihe Hospital,Yunyang Medical College, Shiyan, 442000 China);Relationship between Vascular Growth Factor Levels and Endometriosis[J];Journal of Hubei Institute For Nationalities Medical Edition;2002-02
3 CAO Lixing, HAN Bing, LI Tongxi, et al. The Second Clinical Hospital of Guangzhou University of TCM, Guangzhou 510120;Experimental study of activity of natural kill cell of Promoting blood circulation to dispel stasis, soften and resolve hard mass on endometriosis.[J];Hebei Journal of Traditional Chinese Medicine;2004-04
4 Cao Lixing1,Han Bing2,Li Tongxi2,Ma Pingzhong2No.2 Clinical Medicine College,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong,China,510120No.2 Attached Hospital to Tianjin College of Chinese Medicine,Tianjin,China,300150;The Empirical Study of IL-6 with Promoting Blood Flow to Removing Stasis and Soften Hard Lumps and Dispel Nodes to Treat Endometriosis[J];Journal of Henan University of Chinese Medicine;2007-06
5 Zhao Fang1, Chu Yuxia2, Feng Yinman3(1. Institute of Reproductive Medicine, Luoyang Heath Care Center of Maternity and Children, Luoyang, Hennan, 471000;2. Department of Gynecology and Obstetrics, Henan Hospital of TCM, Zhengzhou, Henan, 450002;3. Zhengzhou Board of Health, Zhengzhou, Henan, 450003);Influence of Daihuang Zhechong Pellet on Immunologic Function of Fxpriental Endometriosis Rats[J];Henan Traditional Chinese Medicine;2008-10
6 LI AijunDepartment of Gynecology and Obstetrics,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052,China;Experimental Study on Mechanism of Treating Endometriosis with Chinese Herb Neiyixiao[J];Journal of Medical Forum;2006-10
7 LIU Suling,YANG Min Luohe The Third People′s Hospital,Luohe 462000,China;Effect of Peritoneal Fluid of Endometriosis Model Rats to Function of Human Sperm and Chinese Herbs Invigorating Kidney to Promote Blood Circulation[J];Journal of Medical Forum;2007-02
8 YANG Min~1,MENG Jun~2 (GuangZhou University of Traditional Chinese Medicine Guangzhou 524023,China);The Effect of Peritoneal Fluid of Endometriosis Model Rats on the Function of Human Sperm and the Effect of Chinese Herbs Invigorating the Kidney to Promote Blood Circulation[J];Acta Academiae Medicinae Jiangxi;2006-03
9 LU Cui yun\+1,QI Rong yi\+1,LU Cui min\+2 (1 Department of obstetrics and gynecology,No.254 Hospital of the Chinese People′s Liberation Army, Tianjin 300142,China;2 Tianjin College of Traditional Chinese Medicine,Tianjin 300193,China);Study on the Effect of YWL on the Lever of Endocrine Hormone of Endometrisosis[J];Liaoning Journal of Traditional Chinese Medicine;2003-03
10 LI Gui LI Gui-zhai JIA Feng-xin WU Da-yong TIAN Peng-xue ZHANG Lei Shijiazhuang Pingan Hospital, Hebei;Effects of “Taohong Tongguan Capsule” on T-cell Subgroup and IL-6 and TNF-α in Patients with Salpingemphraxistic Infertility[J];Shanghai Journal of Traditional Chinese Medicine;2007-05
Chinese Journal Full-text Database 10 Hits
1 Li Wen, Yang Fan, Jin Zhijun, Yang Yunfang (Department of Obstetrics and Gynecology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003);Effect of peritoneal fluid of women with endometriosis on the natural killer cell activity in vitro[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1999-10
2 Peng Xinping, Cui Ying, Guo Feng (Department of Obstetrics and Gynecology,Changhai Hospital,Second Military Medical University,Shanghai,200433);Correlation between red cell immune function and NK cell activity in patient with endometriosis[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1999-03
3 CAI Jiaxing,GAO Qin, SONG Kunling, et al. Qingdao People's Hospital, Qingdao 266001,Shandong Province;Therapeutic effects of Sanjie Zhitong decoction enema on endometriosis[J];HEBEI JOURNAL OF TRADITIONAL CHINESE MEDICINE;2000-01
4 Ren Xingbin,Ji Haisheng,Yin Chaoying;Levels and clinical significance of sICAM-1、sVCAM-1、sCD_(44)V6 of patients with endometriosis[J];Shandong Medical Journal;2005-05
5 Wang Zhilian, Zhang Yongluo, Yue Yue'e, et al (Dept.of Obstetrics and Gynecology 2nd Clinical Medical College ,Shanxi Medical University, Taiyuan 030001);Changes of immune function in women with pelvic endometriosis[J];JOURNAL OF SHANXI MEDICAL UNIVERSITY;1999-03
6 ZHENG Fei, LU Shi ming (Woman's Hospital, School of Medicine, Zhejiang University, Hangzhou,310006);Effects of Interleukin-6 on Basal and FSH-stimulated Secretion of Estrodiol and Progesterone by Human Granulosa Cells in vitro[J];Reproduction and Contraception;2001-02
7 LU Jing WU Rui-fang JIANG Jing XIU He-ming XU Zheng WANG Zhen-hai(Department of Obstetrics and Gynecology, The Second Hospital ofHebei Medical University, Shijiazhuang, 050000) ( Key Laboratory, Bethune International Peace Hospital, Shijiazhuang, 050082);Secretion of Interleukine-6 by Endometrial and Endometriotic Cells in Vitro[J];Reproduction and Contraception;2002-01
8 Li Shuping, Bai Shufang, Sun Jiaqiang. Department of Chinese Medicine , Medical College of Chinese People’s Armed Police Forces.Tianjin 300162;Effects of FU TONG NING decoction and its related formulae on the immune function of endometriosis in rat[J];Acta Academiae Medicinae Cpapf;2000-04
9 Zhu Wenlian;Zhao Lianzhu;Wang Pei (Beijing College of Acupuncture-Moxibustion and Orthopedics and Traumatology, 100015 );Experimental Observation of the Effect of Moxibustion on Macrophage Phagocytic Function in Mice[J];ACUPUNCTURE RESEARCH;1999-02
10 Wang Huimin, Chen Huade (Zhejiang College of TCM, Hangzhou, 310009) a;Clinical Study on Endometriosis Treated by Moxibustion and Point-Injection[J];ACUPUNCTURE RESEARCH;2000-02
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Xia,REN Yanli Zhengzhou Erqi Center of Disease Control,Zhengzhou 450008,China;Clinical Observation on Dan'e Fukang Decocted Extract in Treating Endometriosis[J];Journal of Medical Forum;2008-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved