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《Guangdong Medical Journal》 2001-05
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Study of expression of matrixmetalloproteinases in liver cirrhosis

Liu Jingzhang, Zhao Zilin, Gao Yi, et al. Department of Hepatobiliary, Zhujiang Hospital, First Military Medical University, Guangzhou 510282  
Objective To investigate the relationship between the expression of MMP-1 and MMP-2 in the liver and the development of liver cirrhosis.Methods Expression of MMP-1 and MMP-2 in the liver tissues of 39 patients was studied by Strept Acidin-Biotin-enzyme complex(SABC) immunohistochemistry and computer image analysis. Results Increase expression of matrix metalloproteinases was related to the cirrhosis of liver. In the cirrhotic tissue, the expression of MMP-2 was higher than that in normal tissue( P 0 01); MMP-1 expression in the verge of cirrhosis tissue was not significantly higher than that in normal tissue ( P 0 05).Conclusion Matrix metalloproteinases is one of the important factors influencing the development of cirrhosis of liver with different mechanism in MMP-1 and MMP-2.
【CateGory Index】: R363
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Chinese Journal Full-text Database 10 Hits
1 Yan Xiuying; Xu Zhihua; Han Lisha; et al(Department of Basic Medicine,Baotou Medical College,Baotou 014010);The Inhibitory Effect of Fructus Lycii on Carbon Tetrachloride-caused Peroxidtion Action of Lipid in Rats[J];JOURNAL OF BAOTOU MEDICAL COLLEGE;1998-01
2 WANG Li cun, LI Lin The First Affiliated Hospital, West China University Medical Science (Chengdu,610041,China);Experimental Study of Effect and Principle of Warming Yang Herbs in Rat Model with Liver Fibrosis[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-02
3 Song Jian, Zhang Xingrong, Zhu Liang, Zhang Zhongbing, Zhang Xiankang (Department of Gastrointerology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003);Effect of oxymatrine on fibroblastic proliferation and procollagen mRNA expression[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1999-06
4 ZHANG Rong-hua, ZHOU Zi-cheng, HONG Duo-lun, AI Jiu-song (Department of Traditional Chinese Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038,China);Effects of Panax Notogenseng on CCl4-induced liver fibrosis in rats[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-04
5 XIE Yu Mei 1, NIE Qing He 1, ZHOU Yong Xing 1, ZHU Xiao Hui 2, WANG Jiu Ping 1, DUAN Guo Rong 3 1Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China, 2Department of Patholo;Tissue inhibitors of metalloproteinase-1 and -2 (TIMP-1 and TIMP-2) related antigens expression in liver tissues of patients with liver cirrhosis[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-07
6 Wei Minyi (Department of Pathology, First Affiliated Hospital);A PATHOLOGICAL STUDY ON DIABETIC HEPATOPATHY[J];Journal of Guangxi Medical University;1995-04
7 Xian Su, Huang Song, Su Jianjia, et al. (the First Affiliated Hospital o f Guangxi Medical University, Nanning 530021,China);A STUDY ON EXPERIMENTAL DIABETES ANIMAL MODELS IN TREE SHREWS INDUCED B Y STREPTOZOTOCIN[J];Journal of Guangxi Medical University;2000-06
8 Xian Su,Wang Naizun,Wei Minyi,et al(Dept of Endocrinology,First Affiliated Hospital,Guangxi Medical University\ Nanning\ 530021);THE CLINICAL AND PATHOLOGICAL RESEARCH OF DIABETIC HEPATOMEGALY[J];ACTA ACADEMIAE MEDICINAE GUANGXI;1996-03
9 Li Youyuan; He Fuqing; Peng Xiaoli(Department of Geriatrics, The Second Affilitaed Hospital, Hunan Medical University)Han Liwen(Department of Madicine, The Second Affilitaed Hospital Hunan Medical University);THEPROTECTION OF LIGUSTRAZINE FROM CCl4- INDUCED LIVER FIBROSIS IN RATS[J];BULLETIN OF HUNAN MEDICAL UNIVERSITY;1995-06
10 Zhao Liyun (赵丽云), Ding Xia (丁 霞), Meng Yichun (蒙一纯), et al. (Beijing University of Traditional Chinese Medicine, Beijing 100029);Immunohistochemistry and Image Analysis on the Anti alcoholic Liver Fibrosis Function of Tiaoganlipifang In Rat[J];JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;2000-02
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