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《Guangdong Journal of Health and Epidemic Prevention》 2004-02
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Investigation on antibody level against epidemic cerebrospinal meningitis (Serotype A) among the floating population in Guangzhou

LI Mei xia, ZHOU Xiu zhen, ZHANG Zhi guang, et al. Center for Disease Prevention and Control of Guangzhou, Guangzhou 510080, China  
Objective To define the antibody level against epidemic cerebrospinal meningitis A (ECM A) and the vaccination coverage among floating population in Guangzhou. Results Cross sectional study was employed and 1 026 subjects were recruited by cluster sampling in a development district of Guangzhou. Antibody against ECM A was tested by ELISA and vaccination coverage by structured questionnaire. Results Nine hundred and seventeen persons were antibody positive against ECM A (positive rate 89 28%, GMT 1∶17).Meningococcal polysaccharide vaccination coverage was 17 64%. Antibody positive rate and GMT in vaccinated group were significantly higher then that in unvaccinated group (antibody positive rate 93 90% vs 88 40%; GMT 1∶21 86 vs. 1∶16 11, Z=3 76, P 0 05). Antibody level had significant different in age groups (chisq=27 80, P 0 05). The antibody level and GMT was negatively correlated to age with the highest antibody level in less than 20 years group and the lowest in age 40 and over groups. Conclusion The immunity against ECM A was considerably high in floating population in Guangzhou but the antibody level and the vaccination coverage were low in older age group. It is necessary to implement vaccination program in floating population.
【Fund】: 广东省医学科研基金立项课题 (项目编号A2 0 0 0 60 7)
【CateGory Index】: R181.3
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