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《South China Journal of Preventive Medicine》 2006-03
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Effect of man smoking on serum adhesion molecule and oxidative stress

LI Li,LING Wen-hua.Center for Disease Control and Prevention of Baiyun District,Guangzhou 510300,China  
Objective To observe the effect of man smoking on serum adhesion molecule and oxidative stress.Methods 99 male attendees at local CDC divided into smoking(43) and non-smoking(56) group were examined serum concentration of Intercellular adhesion molecule-1(ICAM-1),Vascular endothelial adhesion molecule-1(VCAM-1),Superoxide dismutase(SOD),Total antioxidative capacity(T-AOC) respectively.Results The sICAM-1 of smoking and nonsmoking group were 855±294 ng/mL and 661±285 ng/mL(P0.01)as well as T-AOC were 11.90±8.64 U/mL and 18.84±11.47 U/mL(P0.01).There was no significant difference in sVCAM-1 and SOD between two groups whereas a significant correlated association in sICAM-1 by smoking index in smoking group(r=0.621,P0.05).Conclusion Cigarette smoking influences serum adhesion molecule and oxidative stress which maybe results in Atherosclerosis.
【CateGory Index】: R163
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