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《Chemical Research In Chinese Universities》 2000-12
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Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues

LIU Jie 1, ZHANG Qian Ling 1, WANG Li Jun 2 WANG En Bo 3, HUANG Jin Wang 1, JI Liang Nian 1  [WT5”BX](1. State Key Laboratory of Ultrafast Laser Spectroscopy, Department of Chemistry, Zhongshan University, Guangzhou 510275, China  
Rare earth molybodogemanium \%2e, 4e \%heteropoly blues, LnH 3[GeMo Ⅵ 10 Mo Ⅴ 2O 40 ]·8H 2O and LnH 5[GeMo Ⅵ 8Mo Ⅴ 4O 40 ]·8H 2O(Ln=La, Ce, Nd, Sm, Gd), have been prepared and characterized by IR, UV, TG DTA, XPS, ESR. It is found that the structures of the heteropoly blues still retain the Keggin structure with a slight difference compared with their un reduced compounds. The in vivo activity of Pr(2) against influenza virus(FM1) in the mice was investigated. Pr(2) was administrated perorally(p. o.) and intraperitoneally(i. p.) to 14—16 g Kunming mice infected with FM1. The results show that in contrast to the positive ribavirin, the curative effect of Pr(2) proved to be better and i. p. administration was more effective than p. o. administration. [WT5HZ]
【Fund】: 国家自然科学基金! (批准号 :3 9870 895 )资助 .
【CateGory Index】: O614
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