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《Chemical Research In Chinese Universities》 2001-09
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A New Diterpene Lactone from the Soft Coral Sarcophyton molle Tix. Dur.

SU Jing Yu, YAN Su Jun, ZENG Long Mei  (Department of Chemistry, Zhongshan University, Guangzhou 510275, China)  
Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C 1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.
【Fund】: 国家自然科学基金 (批准号 :2 9772 0 5 8;2 992 0 30 );; “九五”国家科技专项“南沙群岛及其邻近海区综合科学考察”项目(批准号 :97-92 6 -0 2 -0 3)资助
【CateGory Index】: O629.61
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