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《Chemical Research In Chinese Universities》 2002-09
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Synthesis and Bioactivity of 5-Avermectin B_(1a) Esters

LIAO Lian An 1, LI Zheng Ming 2* , FANG Hong Yun 1, ZHAO Wei Guang 2, CHEN Ming De 1, FAN Zhi Jin 2, LIU Gui Long 2(1. Department of Chemistry, Xiamen University, Xiamen 361005, China; 2. Institute of Emento organic Chemistry, State  
Ten 5 Avermectin B 1a ester derivatives were prepared from avermectin B 1a and carboxylic acids in the systems of DCC/DMAP. Their chemical structures were confirmed by IR, 1H NMR, \{ 13 C NMR\} and MS. Their insecticidal activity was evaluated against Aphis gossypii Glover and Tetranychus truncatus Ehara. It was found that some compounds showed a higher insecticidal activity than Avermectin.
【Fund】: 国家自然科学重点基金 (批准号 :2 983 2 0 5 0 )资助
【CateGory Index】: O629.9
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