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《Journal of Hepatopancreatobiliary Surgery》 2006-03
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Effect of puerariae on NO,ET-1 in rabbits following hepatic ischemia reperfusion injury

WANG Wei~*,XU Dong-wu,WANG Wan-tie~*,et al.* Department of Pathophysiology,Wenzhou Medical College,Wenzhou 325027  
Objective To observe the changes of NO and ET-1 in rabbit's hepatic ischemia reperfusion injury(HIRI) and the effects caused by Puerariae(Pur).Methods The rabbits in the experiments were divided into the following three groups randomly: group C(n=10),group IR(n=10) and group Pur(n=10).NO and ET-1's content of plasma at different time were determined.In the end of the experiments,NO and ET-1's content of hepatic tissue were tested.Morphological changes of HIRI in rabbits and the protective effects of Pur were observed under electron microscope.Results Compared to C group and Pur group respectively in the IR group,NO and ET-1's contents significantly changed at 45 minuter reperfusion.In the Pur group the ultrastructural injury of the ischemia was greatly ameliorated.Conclusion Puerariae can promote releasing of NO and has notable protective effects on HIRI.
【Fund】: 浙江省卫生厅科研基金资助项目(98A087)
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 4 Hits
1 DENG Li-ming,PENG Cheng-jiang,QI Bo,QIN Chuang,LIU Xiao-bo,QIN Yan(College of Clinical Medicine,Dali University,Dali,Yunnan 671000,China);The Protective Effect of Zingiber on Hepatic Ischemia Reperfusion Injury in Rabbits[J];Journal of Dali University;2008-10
2 LUO Hongzhi1, HE Yanzheng2, YU Yuanlong1, HUANG Zonghai3, CHEN Hong1 (1.Department of Postdoctoral Workstation of the People’s Hospital of Zhongshan City, Southern Medical University, Zhong- shan 528400, China; 2.Department of Vascular Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, China; 3.Department of Gastrointestinal Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510515, China);Protective mechanism of ligustrazine on rat liver during ischemical reperfusion injury[J];Journal of Hepatopancreatobiliary Surgery;2009-04
3 LI Shu-cui, LI Qing-zhong,WANG Yuan-fang, LIU Jin-ping, ZHANG Shu-ping (Department of Pharmacology, Binzhou Medical College, Binzhou 256603, China);Protective mechnism of sinomenine on hepatic injury induced by ischemia/reperfusion in rats[J];Progress in Modern Biomedicine;2010-15
4 ZHNAG Fu-zhi1,SHI Lu2,HAO Mao-lin2,WANG Wei2,WANG Wan-tie2(1.The People's Hospital of Pingyang,Pingyang 325400,China;2.Wenzhou Medical College,Wenzhou 325035,China);The Effect of Puerarin on Serum Interleukin-1β and Tumor Necrosis Factor-alpha of Rabbits with Hepatic Ischemia-reperfusion Injury[J];Acta Chinese Medicine and Pharmacology;2011-02
【Citations】
Chinese Journal Full-text Database 2 Hits
1 XIANG Hong Jun 1, ZHAO Zuo Qing 1, LI Ji Peng 2, ZHANG Zhi Pei 1 1Department of Experimental Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China, 2Department of Gastrointestinal Surgery, Xijing Hospital,;Change of concentration of NO, SOD in the blood and the expression of Bax, Bcl-2 in the lung after ischemia-reperfusion of small intestine of the rat[J];Journal of The Fourth Military Medical University;2002-21
2 FANG Fang Zhi 1, WANG Zi Zhen 2, WANG Shui Kui 2, DAI De Zai 1, YANG Wei 1 1Research Division of Pharmacology, China Pharmaceutical University, Nanjing 210009, China; 2 Nanjing Radio Immune assay Center, First Hospital Affiliated Nanjing M;Inhibition of Puerarin on the H_2O_2-induced Apoptosis of Smooth Muscle Cells[J];Journal of China Pharmaceutical University;2002-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 TANG Xing-San~1, MA Ya-Zhen~1, LIU Hong-Yun~1, ZHU Xiao-Qin~2, LEI Shui-Sheng~2 ~1Life Science and Technology College of Xiaogan University, Xiao'gan 432000, China, ~2Department of Anatomy, Tongji Medical College, Huazhong University of Science and Technology, Wu'han 430030, China;Changes of nitric oxide synthesis in cardiac ischemia reperfusion injury[J];Journal of The Fourth Military Medical University;2005-16
2 Zheng- Zhuan Wei and Sui-Sheng Xia Wuhan, China Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;γ-hydroxybutyrate protects the liver from warm ischemia-reperfusion injury in rat[J];国际肝胆胰疾病杂志(英文版);2004-02
3 LI Mei-zhen1,YANG Bao-wei2,HUANG Ming-guang1,3,HU Chuan-shui4,TANG Yin-sheng1,3,HU Chuan-huo2(1.Guangxi Work Station of Livestock&Poultry Breed Improvement,Nanning 530001,China; 2.College of Animal Science and Technology,Guangxi University,Nanning 530005,China; 3.Guangxi Keda Livestock&Poultry Improvement Co.Ltd,Nanning 530001,China; 4.Guangxi College of Agricultural Vocational Techniques,Nanning 530007,China);Preliminary study on effects of two Chinese medicine extracts ligustrazine and puerarin on cryopreservation of boar semen[J];Guangdong Agricultural Sciences;2012-23
4 WU Ying~1,WANG Lu-Ya~2,ZHANG Hui-Xin~1,WANG Wei~3,FANG Wei~1, WANG Wei,and XIAO Lei (1.Department of Pathology,Affiliated Beijing Anzhen Hospital of Capital Medical University;2.Beijing Institute of Heart,Lung and Blood Vessel Diseases; 3.Beijing University of Traditional Chinese Medicine,Beijing 100029,China);The Effect of Total Flavone of Radix Puerariae on Atherosclerotic Plaque Formation of A polipoprotein E Gene Deficient Mice[J];Chinese Journal of Arteriosclerosis;2006-04
5 ZHANG Peng-fei 1,WU Wei-guo 2(1.College of Food Science and Technology,Hu'nan Agricultural University,Changsha,Hu'nan 410128,China; 2.Laboratory for Food Science and Bio-technology of Hu'nan Province,Changsha,Hu'nan 410128,China);The Development of Research in Flavonoids of Puerariae[J];Academic Periodical of Farm Products Processing;2012-03
6 WU Ya-guang,WU Tai-huang,MU Qing-ling,LU Jun,XU Jian,SU Zhong-xue Department of Hepatobiliary Surgery,Shandong Provincial Hospital(Jinan 250021,China);Involvement of nitric oxide(NO) and endothelin(ET) in ischemia-reperfusion injury and its role in preconditioning[J];Chinese Journal of Current Advances in General Surgery;2003-04
7 Wu Yaguang,Wu Taihuang,Mu Qingling,et al;Effect of preconditioning on serum nitric oxide and endothelin in rats with ischemia-reperfusion injury[J];Shandong Medical Journal;2003-35
8 WANG Xue-mei,ZHANG Yun-fei,LI Hong,DAI Di,ZHANG Qian-qian,LI Xiao-shu(Department of Ultrasound,The First Affiliated Hospital of China Medical University,Shenyang 110001,Liaoning,China);Value of color Doppler ultrasound in measuring flow volume towards liver after liver ischemia reperfusion[J];Biomedical Engineering and Clinical Medicine;2012-04
9 LI Shu-cui, LI Qing-zhong,WANG Yuan-fang, LIU Jin-ping, ZHANG Shu-ping (Department of Pharmacology, Binzhou Medical College, Binzhou 256603, China);Protective mechnism of sinomenine on hepatic injury induced by ischemia/reperfusion in rats[J];Progress in Modern Biomedicine;2010-15
10 QIE Wen-bin, TU Wei-feng, DAI Jian-Qiang, YU Dong-nan, SHI Chong. Department of Anesthesiology, Guangzhou General Hospital, Guangzhou Command, Guangzhou 510010, China;Effects of impaired oxidation-antioxygen system on lung injury induced by gut ischemia-reperfusion in rats[J];The Journal of Practical Medicine;2009-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Binbin △, YU Shifeng (Department of Oral Pathology, Peking University School of Stomatology, Beijing 100081,China);Effect of puerarin on the bone metabolism in vitro[J];Journal of Beijing Medical University;2003-01
2 YAN Fu-ling*, LU Guo*, WANG Ya-qiong*, HONG Zhen. *Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, ChinaCorresponding author: HONG Zhen, Email: zhong@shmu.edu.cn;Effect of puerarin on the expression of Aβ_(1-40) and Bax in brain of AD rats induced by Aβ_(25-35)[J];Chinese Journal of Neuromedicine;2006-02
3 LIU Hai yan, SHI Yuan gang (Department Nutrition and Food Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China);Effects of puerarin on the levels of PGI_2 and TXA_2 in plasma of rats with hyperlipidemia[J];Acta Academiae Medicinae Militaris Tertiae;2004-11
4 XIANG Hong Jun 1, ZHAO Zuo Qing 1, LI Ji Peng 2, ZHANG Zhi Pei 1 1Department of Experimental Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China, 2Department of Gastrointestinal Surgery, Xijing Hospital,;Change of concentration of NO, SOD in the blood and the expression of Bax, Bcl-2 in the lung after ischemia-reperfusion of small intestine of the rat[J];Journal of The Fourth Military Medical University;2002-21
5 ZHAO Shu-Jie,HAN Mei,HAN Zhong-Ming,LI Yan-Ying,YANG Li-Min(College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118);Separation and Identification of Flavonoids from Smilacina Japonica by High Speed Counter-Current Chromatography[J];Chinese Journal of Analytical Chemistry;2009-09
6 JIANG Yong,QIU Yu-dong,GU Xiao-ping,et al. Department of Hepatobiliary Surgery,Gulou Hospital Attached to Medical College of Nanjing University,Nanjing 210008;Experimental research of ischemic preconditioning on the protective effect of the recipient after liver transplantation in rats[J];Journal of Hepatopancreatobiliary Surgery;2004-03
7 XIANG Yang, CAI Duan. Department of General Surgery, Huashan Hospital Affiliated to Fudan University, Shanghai 200082;Discussion on the protective effect of liver preconditioning on liver transplantation in rat[J];Journal of Hepatopancreatobiliary Surgery;2006-01
8 SHI Wei-hai, LI Wen- mei.Department of General Surgery, Affiliated Wujin Hospital of Jiangsu Univercity, Changzhou 213000;Experimental study on the action and mechanism of delayed protection of ischemic preconditioning on liver ischemia/reperfusion injury in rats[J];Journal of Hepatopancreatobiliary Surgery;2006-02
9 SHI Yang,QIAN Haixin,QIN Lei,et al.Department of General Surgery,the First Hospital Affiliated to Suzhou University,Suzhou 215006;Changes of nitric oxide and nitric oxide synthase during hepatic ischemia/reperfusion of rat[J];Journal of Hepatopancreatobiliary Surgery;2008-01
10 XU Yixiao,JIN Keke,WANG Wantie,et al.Department of Pathophysiology,Wenzhou Medical College,Wenzhou 325035;Inhibitory effects of ischemic preconditioning plus tetramethylpyrazine on apoptosis of hepatic cell after intestinal ischemia reperfusion in rats[J];Journal of Hepatopancreatobiliary Surgery;2008-01
【Secondary References】
Chinese Journal Full-text Database 5 Hits
1 QIN Yandi1,WEI Xiaomei1,WANG Xiaoli1,ZHU Ling1,CAO Xue1,SU Juan2,QIN Yan2(1.Clinical College,Dali University,Dali,Yunnan 671000,China;2.Pre-clinical College,Dali University,Dali,Yunnan 671000,China);Protective Effect of Zingiber on Kidney Injury Induced by Diabetes in Mice[J];Journal of Dali University;2013-06
2 ;Mechanism and Prevention of Hepatic Ischemia-reperfusion Injury[J];Journal of Henan University of Science & Technology(Medical Science);2012-03
3 LU Ren-fu, JA Ke, HOU Peng-yuan, WU Qing-chen (Dept. of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China);Effects of Ethanol Extract of Zingiber officinale against Myocardial Ischemia-reperfusion Injury in Rats[J];China Pharmacy;2010-11
4 LI Shucui,MA Yuli,WANG Yuanfang(School of Pharmacy,Binzhou Medical University,Yantai 264003,China);Protective effects of Sinomenine on mice brain cells after ischemia-reperfusion injury[J];Medical Research and Education;2012-05
5 Zeng Xiaoping;Shan Guigen;Chen Xiaorui;;Study on Optimum Process for Extraction of Total flavonoids from Gossampinus Malabaria Leaf[J];China Journal of Pharmaceutical Economics;2013-06
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 ZHU Qing Lei,HE Ai Xia ,LU Xin Ran ( Applied Pharmacology Laboratory, Weifang Medical College,Weifang 261042,Shandong) ( Department of Anesthesiology,The Affiliated Hospital of Weifang Medical College,Weifang 261031,Shandong);Effects of Puerarin on the Scavenge of Oxygen Free Radicals and the Antagonism Against Oxidative Injury[J];Pharmaceutical Journal of Chinese People's Liberation Army;2001-01
2 Liu Qigong; Wang Lin;Lu Zaiying et al.(Department of Cardiology,Tongji Hospital,Tongji Medical University,Wuhan 430030);The protective effect of Puerarin on ischemic myocardium in dogs and its possible mechanism[J];JOURNAL OF CLINICAL CARDIOLOGY;1998-05
3 WANG Wan-Tie, LIN Li-Na, XU Zheng-Jie, LI Dong, WANG Zhong-Min Department of Pathophysiology, Wenzhou Medical College, Wenzhou(325003);Role of oxygen free radicals in reperfusion injury following hepatic ischemia and effect of ligustrazin[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1999-01
4 Chang Zhiwen,Liu Qi (Tongren Hospital,Capital University of Medical Sciences,Beijing 100730);APOPTOSIS OF CARDIAC MYOCYTES IN ISCHEMIC AND REPERFUSED RATS AND THE INTERFERENCE OF DRUG[J];CHINESE NEW DRUGS JOURNAL;2000-01
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