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《Journal of Hepatopancreatobiliary Surgery》 2012-06
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Study on risk factors of severe pancreatitis complicated with lung injury

CHEN Qiu-xing,LV De-chao,CAO Bin,et al.Department of Emergency Surgery,Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001,China  
Objective Toexplore riskfactors ofsevere acutepancreatitis(SAP)complicated with acute lung injury(ALI) in the acute phase.Methods A retrospective analysis was conducted in 107 patients,the variables included the different CT types,physiological index in 24 h after admission,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score and duration of the systemic inflammatory response syndrome(SIRS).The correlation of acute lung injury with these variables was studied,and the independent risk factors of acute lung injury in SAP were explored using the single factor chi-square test analysis and unconditional multivariate Logistic regression analysis.Results Thirtynine cases developed to acute lung injury in 107 SAP patients,and ARDS occurred in 16 cases.There was a significant correlation between ALI/ARDS occurrence and the cause of SAP,medical history,CT classification,SIRS time,APACHE Ⅱ score,calcium ion(Ca2+) concentration,albumin(ALB) concentration,blood sugar concentration(GLU),white blood cell count(WBC) and neutrophils count(PMN).Albumin concentration,calcium ion concentration and SIRS went into unconditional multivariate Logistic regression analysis equation.Conclusion The study shows the ALI/ ARDS incidence in SAP is 36.45%.ALB concentration,Ca2+concentration and SIRS are independent risk factors of SAP complicated with ALI.
【CateGory Index】: R657.5
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