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《Academic Journal of Guangdong College of Pharmacy》 2003-01
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Experimental study on anti-aging effect of Ginsenosides on skin of the aging model mice induced by D-galactose

WANG Hong li 1, WU Tie 2, WU Zhi hua 2, ZHU Yong xiang 3, GUO Qi jie 1 (1.Department of Dermatology, Guangdong College of Pharmacy, Guangzhou,Guangdong 510224; 2.Department of Pharmacology, Guangdong Medical College, Zhanjiang,Guangdong 524023)  
Objectives: To investigate the anti aging effect of Ginsenosides on skin. Methods: The aging mice model were established by subcutaneous administration with a dose of D galactose(1000 mg/kg·d -1 ) to female mice for 6 weeks. In the mean time,the mice received Ginsenosides(100 mg/kg·d -1 or 50 mg/kg·d -1 ) by intragastric administration. After 42 days, the SOD activity, the MDA and hydroxyproline contents in skin and the CAT and GSH Px activities in whole blood were determined. Results: The results showed that with the dosage of 100 mg/kg·d -1 Ginsenosides could significantly increase the SOD activity in skin and the CAT and GSH Px activities in whole blood,decrease the content of MDA in skin and increase the gydroxyproline content of dermal tissue in model mice. Conclusions: Ginsenosides(100 mg/kg·d -1 ) has obvious anti aging effects on aging mice's skin.
【CateGory Index】: R285.5
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Chinese Journal Full-text Database 10 Hits
1 LEI Xiu-juan1,FENG Kai2,SUN Li-wei2,JIANG2 Rui,LI Chang-yu1,WANG Ying-ping1(1.Institute of Special Economic Animal and Plant Science,CAAS Jilin 132109;2.Life Science Center of Beihua University,Jilin 132013,China);Progress in Studying Anti-Aging Mechanism of Ginsenoside[J];Amino Acids & Biotic Resources;2010-01
2 Wang Yan, Ma Wenqiang;Research advance of the biological functions of ginsenoside[J];Feed Industry;2006-06
3 ZHANG Peng1a,1b,SHEN Hai-long1a,1b,LIU Ji-sheng2 (1a. College of Forestry; 1b. Key Laboratory of Forest Tree Genetic Improvement and Biotechnology,Ministry of Education,Northeast Forestry University,Harbin 150040,Heilongjiang,China; 2. College of Agriculture,Yanbian University,Longjing 133400,Jilin,China);Effects of Nurturing Age and Edge Effect on Root Bark Yield of Aralia elata[J];Nonwood Forest Research;2009-02
4 ZHANG Peng,SHEN Hai-long(College of Forestry,Northeast Forestry University,Harbin 150040,Heilongjiang,China);Cultivation techniques of Aralia elata planted for edible and medicinal purposes[J];Nonwood Forest Research;2011-03
5 XU Xiao-yue,ZHANG Guang-wei,LI Zhan,ZHOU Ji-chun,LI Feng-chun,YANG Hai-yan,HE Yan (Henan Provincial Institute of Food and Drug Control,Zhengzhou 450003,China);Experimental study of Eguiyangxue Syrup on facial beatification[J];Journal of Henan University(Medical Science);2009-01
6 LI Ruo-nan1),GUI Li1),LI Shu-de2),GUO Jia-zhi3),MA Yun-bing4)(1)Dept.of Diabetes,The Third People's Hospital of Yunnan Province,Kunming Yunnnan 650011;2)Dept.of Biochemistry,Kunming Medical University,Kunming Yunnan 650031;3)Dept.of Anatomy,Kunming Medical University,Kunming Yunnnan 650031;4)Dept.of Osteology,The Third People's Hospital of Yunnan Province,Kunming Yunnnan 650011,China);Panax Notoginseng Saponin Regulates c-Jun N-terminal Kinase to Improve Insulin Resistance of Rat Liver Tissue[J];Journal of Kunming Medical University;2012-04
7 XU Bai~1 SHEN Yun-qi~2 FANG Xiao-ling~2 ZHA G Li-jun~2 CHEN Da-wei~1 (1 Department of Pharmaceutics,School of Pharmacy,Shenyang Pharmaceutics University,Shenyang 110016,China; 2 Department of Pharmaceutics,School of Pharmacy,Fudan University,Shanghai 200032,China);Study on preparation and transdermal drug delivery of saponins of panax notoginseng compound liposomal gel[J];Chinese Journal of Clinical Pharmacy;2007-03
8 BAI Zhi-hua,FANG Xiao-ling(Department of Pharmaceutics,School of Pharmacy,Fudan University,Shanghai 200032,China);Anti-aging effect of microemulsion containing Panax notoginseng on skin[J];Chinese Journal of Clinical Pharmacy;2007-04
9 XIA Jin-ming,ZHANG Ying,KANG Ting-guo,et al(Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China;2.Shenyang DongXin Pharmaceutical Co,Ltd,Shenyang 110032,China);Experimental study of anti-ageing effect of active phospholipids on skin[J];Practical Pharmacy and Clinical Remedies;2007-01
10 ;The research status of traditional Chinese medicine on delaying skin senility[J];Chinese Journal of Aesthetic Medicine;2006-02
Chinese Journal Full-text Database 3 Hits
1 Gao Nannan; Yu Shuren; Liu Ruihong; et al(Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing);Beneficial Effect of Gastrodia on Some Aging Disorders Induced by D-Galactose in Mice[J];Chinese Traditional and Herbal Drugs;1994-10
2 Gong Guoqing, Xu Fuben Department of Pharmacology;Study of Aging Model in Mice[J];Journal of China Pharmaceutical University;1991-02
3 Tian Qinglai;Yin Ying Department of Biology, Peking University, Beijing 100871;Realtionship Between Hydroxyproline and Aging[J];;1991-03
Chinese Journal Full-text Database 10 Hits
1 KONG Xiao-wei~(1,2),LIU Ting-yi,GUAN Jian (1.School of Life Science,Anhui University,Hefei 230039,China; 2.Anhui Key Laboratory of Eco-engineering and Bio-technique,Hefei 230039,China);Effect of polysaccharide from the Gastrodia elata Blume on metabolism of free radicals in subacute aging model mice[J];Journal of Anhui University(Natural Sciences);2005-02
2 GUAN Jia qi,DANG Hai xia,WANG Wei Tutor:Professor ZHANG Ming wei,Associate Professor WANG Ming yan (Nanjing University of Traditional Chinese Medicine,Jiangsu Nanjing 210029,China);DELAYING SENILITY EFFECT OF DRIED REHMANNIA GLUTINOSA LIBOSCH IN JINKUI SHENQI PILL[J];Journal of Anhui Traditional Chinese Medical College;2002-02
3 WEI Liang-yu1,ZHAO Li-hua1,CHEN Huang1,YANG Ke2,ZHOU Fang2,HUANG Yan2 (1The First Affiliated Hospital of Guangxi TCM University,Nanning 530023,China;2Guangxi TCM University,Nanning 530023,China);Effects of moxa cone moxibustion on learning and memory,oxidation resistance of cerebral tissues in senile mice induced by D-galactose[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-08
4 Xu Qingrion,Shen Yunxiu,Sun Yihua, et al (Department of pharmacology,Binzhou Medical College,Binzhou,Shandong 256603);INFLUENCE OF HONGBAO WINE COMPLEX ON CONCENTRATION OF HYDROXYPROLINE[J];JOURNAL OF BINZHOU MEDICAL COLLEGE;2000-04
5 Li Fuen,et al (Department of Biochemistry,Binzhou Medical College,256603);STUDY OF EFFECT OF GYNOSTEMMA COMPLEX ON PROLONGING LIFE[J];JOURNAL OF BINZHOU MEDICAL COLLEGE;1997-05
6 CHEN Zhi-hong, YANG Guo-jun (Department of Human Anatomy,Chengde Medical College, Hebei Chengde 067000, China);STUDY ON THE CHANGES OF MONOAMINE NEUROTRANSMITTER CONTENTS IN HYPOTHALAMUS OF AGING RATS[J];Journal of Chengde Medical College;2005-02
7 YANG Guo-jun, CHEN Zhi-hong, PANG Xiao-jing(Chengde Medical College, Hebei Chengde 067000, China);STUDY ON THE CHANGES OF MONOAMINE NEUROTRANSMITTER CONTENTS IN HIPPOCAMPUS OF AGING RATS[J];Journal of Chengde Medical College;2005-03
8 PANG Xiao-jing,CHEN Long,GAO Fu-lu (Basic Medicl Institute of Chengde Medical College,Hebei Chengde 067000,China);EFFECTS OF HESHOUWU DECOCTION ON MORPHOLOLY OF SENILE RATS KIDNEY[J];Journal of Chengde Medical College;2009-01
9 LIU Xian-ming,LI Yue-fen,LI Guo-ping(Department of Neurosurgery,Municipal Hospital of Qingdao,Qingdao 266071,China);Anti-aging effects of theanine on aging model mice induced by D-galactose[J];Journal of Traumatic Surgery;2008-03
10 FENG Ming-gong, et al (Medical College of Dalian University, Dalian 116622, China);The Effect of D-Galactose on Splenolymphocytes and its Function of Mice[J];JOURNAL OF DALIAN UNIVERSITY;2000-02
China Proceedings of conference Full-text Database 1 Hits
1 LI Chunsheng,Dong Hongbin,LI Diandong and Li zhaohe.China Academy of Traditional Chinese Medical Sciences,Xiyuan Hospital,Beijing China(100091);Chinese Traditional Anti-aging Drug Screening Status And Problems[A];[C];2013
Chinese Journal Full-text Database 10 Hits
1 Chen Zhongfu, Gu Huijue, Wang Linhua, Pan Xingshi Institute of Genetics. Fudan University, Shanghai Institute for Pediatric Research Acknowledgement : The nematode strain DH26 used in tins work was provided by the Caeno-rhabditis Genetics Center, which is funded by the NIH National Center for Research Resources (NCRR).;INHIBITORY EFFECTS OF THREE CHINESE ANTI-SENILITY TONICS ON THE SOS RESPONSE IN E. COLI AND THEIR INFLUENCE ON THE LIFE-SPAN OF C. ELEGANS[J];Carcinogenesis,Teratogenesis and Mutagenesis;1991-03
2 Ma Aiguo 1,Andrew R.Collins 2,Susan J.Duthie 2 1Department of Human Nutrition,Qingdao Medical College,Qingdao 266021, 2The Rowett Research Institute,U.K.;THE DIFFERENCES OF DNA DAMAGE AND REPAIR BETWEEN SEVERAL TYPES OF CELLS[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1997-03
3 LI Xu-dong~1,JIA Rong~1,LU Sa-yin~2,TANG Wen-zhong~1(1.School of Life Science,Anhui University,Hefei 230039,China;2.Center of Moden Experiment Technology,Hefei 230039,China);The effects of pH values on the production of Mn-dependent peroxidase by Schizophyllum sp.F17 in different buffer systems[J];Journal of Anhui University(Natural Sciences);2006-05
4 Wen Han et al (Department of Bioengineering, Anhui Agricultural University, Hefei 230036);Preliminary Study on the Free Radical-Scavenging Activity of Gynostemma Extraction[J];Journal of Anhui Agricultural Sciences;2001-01
5 Qing Yaping et al (Hubei Agricultural College, Jingzhou,Hubei 434025);Study on Tissue Culture and Quickly Reproduction Technology of Aralia mandshurica[J];Journal of Anhui Agricultural Sciences;2004-01
6 ZONG Liang-gang et al (College of Resources and Environmental Sciences,Nanjing Agricultural University,Nanjing,Jiangsu 210095);Study and Prospect of the Pollution of Heavy Metal in Traditional Chinese Medicine[J];Journal of Anhui Agricultural Sciences;2006-03
7 LI Zhu-ying et al(Yuxi Agricultural Institute,Yuxi,Yunnan 653100);Formalization Cultural Technique of Schizophyllum ocmmuner Fr.[J];Journal of Anhui Agricultural Sciences;2007-03
8 LIU Shao-xia et al(Institute of Biological Technology,Shenyang Agricultural University,Shenyang,Laoning 110161);Study on Cultivation Technology of Wild Ginseng under Forest[J];Journal of Anhui Agricultural Sciences;2007-08
9 ZHANG Lei et al(Key Laboratory for Terrain-Machine Bionics Engineering of MOE,School of Biological and Agricultural Engineering,Jilin University,Changchun,Jilin 130022);Relationship between the Ecological Factor and Transpiration Rate of Ginseng under Forest[J];Journal of Anhui Agricultural Sciences;2007-12
10 ZHANG Cai-ying(College of Life Science and Technology,Nanyang Normal University,Nanyang,Henan 473061);Comparison Study on the Physico-chemical Characteristics of Superoxide Dismutase from Different Sources[J];Journal of Anhui Agricultural Sciences;2007-15
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LIU Shao-xia et al(Institute of Biological Technology,Shenyang Agricultural University,Shenyang,Laoning 110161);Study on Cultivation Technology of Wild Ginseng under Forest[J];Journal of Anhui Agricultural Sciences;2007-08
2 ZHANG Ya-yu (Institute of Special Wild Economic Animal and Plant Science,CAAS,Zuojia,Jilin 132109);Discussion on the Development Way of Ginseng Cultivation Industry[J];Journal of Anhui Agricultural Sciences;2008-20
3 LEI Xiu-juan1,FENG Kai2,SUN Li-wei2,JIANG2 Rui,LI Chang-yu1,WANG Ying-ping1(1.Institute of Special Economic Animal and Plant Science,CAAS Jilin 132109;2.Life Science Center of Beihua University,Jilin 132013,China);Progress in Studying Anti-Aging Mechanism of Ginsenoside[J];Amino Acids & Biotic Resources;2010-01
4 YAO XinWu LIU ChangXia ZHANG Peng(College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China);Optimization of the multiple emulsion formulation of gentiopicroside liposome using response surface methodology[J];Journal of Beijing University of Chemical Technology(Natural Science Edition);2012-02
5 ZHOU Ying-wu,PENG Gui-ying,GE Dong-yu,QIU Ze-ji,GU Li-gang (Key Laboratory of Chinese Medicine on Viral Infectious Diseases of Ministry of Education,Beijing University of Chinese Medicine,Beijing 100029,China);Immunological regulation of ginsenoside Rg1 in ovalbumin-immunized BALB/c mice[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-05
6 LENG Jing1,FU Chaomei1,ZOU Liang2(1.School of Chinese Pharmacy,Chengdu University of Tranditional Chinese Medicine,Chengdu 610075,China;2.College of Biotechnology Industry,Chengdu University,Chengdu 610106,China);Progresses on Transdermal Drug Delivery System of Traditional Chinese Medicine[J];Journal of Chengdu University(Natural Science Edition);2008-03
7 CHEN Yong, SUN Ai-min, CHEN Zhi-xian, LIU Ying, CHEN Long-hua, YUAN Ya-wei Department of Radiotherapy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Ginsenoside Rg1 protects rat hippocampal neurons from radiation injury by regulating NOS activity[J];Journal of Southern Medical University;2010-07
8 HE Bai-yin1,LIU Chang-qing1,XIE You-liang1,2,JIANG Dong-xu1,2,CHEN Jian-nan1,2,LIU Fang-yi1(1.Department of New drug R&D in Guangzhou University of Traditional Chinese Medicine,Guangdong Guangzhou 510006,China;2.Dongguan Mathematical Engineering Academy of Chinese Medicine,Guangzhou University of Chinese Medicine,Dongguan,Guangdong 523808,China);Study on percutaneous absorption of ginsenoside Rg1 in total saponins from Panax notoginseng through intact skin[J];Journal of Guangdong Pharmaceutical College;2010-06
9 LIN Shao-bin,LIN Zhen-qunDepartment of Gastroenterology,The People's Hospital of Punin City,Punin 515300,China;The curative effect of Sijunzhi Decoction on patients with diarrhea-predominant irritable bowel syndrome and to the influence of the serum IL-1β,IL-8[J];Acta Medicinae Sinica;2007-02
10 LI Jia-Wang,SI Min-Zhen(Institute of Spectrum Applied Technigue,Chuxiong Normal University,Chuxiong 675000,China);A Study on the Effect of Irradiation on Components in Panax ginseng Powder Using Fourier Transform Infrared(FTIR)Spectrocopy[J];The Journal of Light Scattering;2011-01
China Proceedings of conference Full-text Database 1 Hits
1 An lilong,XiaoMei Zhang TuBao,Dong XiFang,Xu YingMei(college of Agriculture,GuangDong Ocean University,Zhanjiang Guangdong 524008,China);Effect of Different Concentration Neonatal Bovine Serum on the Growth and Proliferation of Primordial Germ Cells(PGCs) from Three-Yellow Broilers[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Zhou Xiang et al;Determination of pjasma lipid peroxides and their physiological significance[J];;1985-04
2 Yang Jingping and Zhou Xiang;Micro-assay of serum and tissue superoxide dismutases Chemoluminescence[J];;1987-01
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