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《Academic Journal of Guangdong College of Pharmacy》 2005-01
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Pharmacological study of the acetone extract from Morus alba L. on respiratory system

FENG Bing-hong,SU Hao-chong,YANG Jun-jie (1.Guangdong College of Pharmacy, Guangzhou 510240, China)  
Objective To study the effect of the acetone extract from Morus alba L. on respiratory system. Methods Relieving a cough and eliminating expectoration were observed by strong aqua spray and phenol red determining methods. The anti-inflammation was studied by ear swelling induced by xylene. Acetycholine was used to induce the guinea pig model of asthma. The content of NO was determined by method of nitrate reductase chromatometry in plasma and trachea tissue. Results The acetone extract of Morus alba L. could significantly decrease cough times and had antiasthma effects. It inhibited ear swelling, increased phenol red output in trachea. The extract could not significantly affect the content of NO in plasma, but could significantly increase the content of NO in trachea tissue. Conclusion The effect of Morus alba L. has the functions of removing the phlegm, anti-inflammation, relieving a cough and antiasthma. The mechanism of antiasthmatic action may be related to the increase of NO in trachea tissue.
【CateGory Index】: R285
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