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《Academic Journal of Guangdong College of Pharmacy》 2005-02
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Optimized separation conditions for the determination of encapsulation efficiency of liposome-encapsulated capsaicin

HONG Hui~1,LONG Xiao-ying~(1,2#),LI Li-ren~1,LIN Dan~1,LIANG Shao-hua~1(1.Department of Pharmaceutics, Guangdong College of Pharmacy,Guangzhou 510240,China; 2.Key Laboratory of pharmaceutics of Chinese Materia Media,Nanfang Medical University,Guangzhou 510515,China)  
Objective To optimize the separation conditions for the detection of encapsulation efficiency of liposome-encapsulated capsaicin on Sephadex G50 mini-column. Method The effects of water content of the gel, centrifuge speed and time on the measurement of encapsulation efficiency were investigated using UV absorbance of the eluate as standard. Result When Sephadex G50 was centrifuged at 1 000 r/min for 6 s for removing 3 ml of water, then at 2 000 r/min for 5 min, liposome-encapsulated capsaicin was separated thoroughly from the gel and free capsaicin remained in the column. Conclusion Proper water content of the gel, suitable centrifuge speed and time are helpful for the separation of liposome-encapsulated capsaicin from the free capsaicin on the column.
【Fund】: 广州市科技局科技攻关课题(编号: 2003Z3-E5121)
【CateGory Index】: TQ460.1
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【References】
Chinese Journal Full-text Database 10 Hits
1 GU Ji-jin,DENG Ying-jie(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang,Liaoning 110016,China);Preparation of curcumin liposomes and its oral pharmacokinetics in rats[J];Journal of Chengdu Medical College;2010-02
2 LU Xiu-xia,LONG Xiao-ying,DING Gang,YUAN Fei,CHEN Jin-ai,CHEN Qiu-wei,ZHANG Hai-long(Department of Traditional Chinese Medicine,Guangdong Pharmaceutical College,Guangzhou,Guangdong 510006,China);Preparation and quality evaluation of capsaicin nanoemulsion[J];Journal of Guangdong Pharmaceutical College;2009-01
3 XI Yu-bin,WU Yun-fu,CHEN Gang(Emergency Department of Suzhou Municipal hospitals,Suzhou,Jiangsu 215001,China);Study on the preparation of cycloicaritin liposomes and their physic-chemical properties[J];Journal of Guangdong Pharmaceutical College;2010-06
4 YAN Zhi-Hong LONG Xiao-Ying TANG Rui RONG Hui-Si HUANG Wei-Min (College of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,P.R.China);Determination of Capsaicin Concentration in Rat Tissues by Fluorescence Spectrometry[J];Chinese Journal of Spectroscopy Laboratory;2006-02
5 Shao Yue;Ling Jiajun;Deng Shanshan;Guangzhou University of Chinese Medicine;;Determination of Entrap ment Efficiency of Gefitinib Liposomes by Mini-column Centrifugation Reversed phase High Performance Liquid Chromatography[J];Journal of North Pharmacy;2015-01
6 ZHU Kun (Department of Chemistry,Jiangsu Institute of Education,Nanjing,Jiangsu,210013,China);Separation Methods and the Determination Methods of Entrapment Efficiency of Liposomes[J];Journal of Jiangsu Institute of Education(Natural Science);2009-02
7 GENG Ye-hui,YANG Li,YOU Jin-song,ZHANG Yu(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Preparation of solid lipid nanoparticles containing praziquantel[J];Journal of Shenyang Pharmaceutical University;2008-01
8 GAO Yuan-yuan,ZHANG Wei-nong(College of Food Science and Engineering,Wuhan Polytechnic University,Wuhan 430023,China);Progress of preparation and detection on liposomes[J];Journal of Wuhan Polytechnic University;2010-03
9 WEI Rui-ping,WANG Qiu-yun,ZHU Wen-chuan,CHEN Yu-shuang(Shanghai Asia Pioneer Pharmaceuticals Co.,Ltd,Shanghai 201203,China);Determination of entrapment efficiency of amphotericin B liposome by mini-column centrifugation-HPLC[J];Chinese Journal of Pharmaceutical Analysis;2009-03
10 Wang Aiping1,Gao Dalin1,Li Yan1,Qi Yuankai1,Mu Hongjie1,Wan Fang2(1.Pharmacy College,Yantai University,Yantai,Shandong,China 264005;2.Katokichi Quality Control Center,Qingdao,Shandong,China 266200);Study on Solid Lipid Nanoparticle as Carrier for Transdermal Delivery of Salicylic Acid[J];China Pharmaceuticals;2012-02
【Citations】
Chinese Journal Full-text Database 5 Hits
1 BAI Ming 1, ZHANG Heng-shu 1, WANG Kun 2, CAI Zhen-xiong 3, JIANG Liang-quan 3 (1. Department of Cosmetic Plastic Surgery, The First Affiliated Hospital to Chongqing University of Medical Sciences, Chongqing 400016, China; 2. Department of Pathogenical Biology of The Third Military Medical University, Chongqing 400038, China; 3. Chongqing CoMed Nano Pharma Co.,Ltd.,Chongqing 400030, China);In vitro study on diffusion of liposomal capsaicin through the human scar skin[J];Journal of Shenyang Pharmaceutical University;2004-01
2 ZHANG Xuan, ZHANG Qiang, QI Xian rong (Department of Pharmaceutics, School of Pharmaceutical Science, Peking University, Beijing 100083, China);STRUCTURE CHARATERISTICS OF INSULIN LIPOSOMES[J];Acta Pharmaceutica Sinica;2001-06
3 GUO Jian xin,PING Qi neng,ZHANG Lei (Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009,China);Studies on hypoglycemic effects of insulin flexible liposomes after transdermal delivery in mice[J];Chinese Pharmaceutical Journal;2001-01
4 GAO Xiao-li,JI Xing-mei (Department of Pharmaceutics,School of Pharmacy,Xinjiang Medical University,Urumuqi 830054,China);Determining the trap efficiency of liposome using sephadex column chromatography[J];Chinese Pharmaceutical Journal;2003-07
5 LONG Xiao-Ying1, OU Shao-Ying2, LUO Jia-Bo1(1. Dept. of Chinese Traditional Medicines, First Military Medical University, Guangzhou 510515;2. Dept. of Pharmaceutical, Guangdong Pharmacy College, Guangzhou 510240);Preparation and Percutaneous Penetration Effect through Excised Mice Skinof Diclofenac Sodium Flexible Liposomes[J];Chinese Journal of Pharmaceuticals;2004-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 XU Bin et al(Jilin Medical Collage,Jilin,Jilin 132013);Antioxidant Effect of Physalis alkekengi Extracts to Rats with High Fat Diet[J];Journal of Anhui Agricultural Sciences;2011-30
2 ZANG Hong Mei, NI Hong Chang, LI Jun (School of Pharmacy, Anhui Medical University, Heifei 230032);Progress in study of insulin liposomes in treating diabetes[J];Anhui Medical and Pharmaceutical Journal;2004-02
3 LI Jin-ming,ZHANG Yan-zhuo,LI Xin (Department of Pharmaceutics,Harbin University of Commerce,Harbin,Heilongjiang Province 150076,China);Optimization of the preparation and prescription of long circulating liposomes of etoposide[J];Anhui Medical and Pharmaceutical Journal;2008-06
4 GUI Shuang-ying,WEN Zhi-qiang,PENG Dai-yin,KAI Wei-hua(Department of Pharmacy,Anhui College of Traditional Chinese Medicine & Anhui "115" Innovation Team for Research and Development of modern Chinese Materia & Anhui Engineering Research Center for Modern Chinese Materia Medica,Anhui Hefei 230031,China);Determination of Entrapment Efficiency of Tetrandrine Liposomes[J];Journal of Anhui Traditional Chinese Medical College;2009-05
5 GU Ji-jin,DENG Ying-jie(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang,Liaoning 110016,China);Preparation of curcumin liposomes and its oral pharmacokinetics in rats[J];Journal of Chengdu Medical College;2010-02
6 HU Yu-Jia,ZHANG Zhong-Yi,LI Hong-lei,ZHANG Shou-Yao* Department of Pharmacy,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China;Preparation of tanshinone transfersome and its deformability[J];Journal of Southern Medical University;2006-03
7 WU Xiao-ning 1,WANG Jun 2,OUYANG Wu-qing 1 (1.College of Animal Science and Technology,Northwest A & F University,Yangling,Shaanxi,712100,China; 2.Shannxi Xi'an Hengtong Guanghua Limited Company,Xi'an,Shaanxi,710068,China);Progress on Liposome in Biological Area[J];Progress In Veterinary Medicine;2005-06
8 GUAN Qing-Xiang1,ZHU Kun2,LIN Tian-Mu1,GUAN Qing-Tao2,GUO Jie3,YIN Jian-Yuan1(1.School of Pharmacy,Jilin University,Changchun 130021,China;2.China-Japan Union Hospital,Jilin University,Changchun 130033,China;3.School of Public Health,Jilin University,Changchun 130021 China);Preparation,Characterization and Drug Release of Biodegradable Solid Lipid Nanoparticles[J];Chemical Journal of Chinese Universities;2010-11
9 <author>NG Guanyin SONG Wenxia Yunfu people's hospital in Guangdong 527300, China;<title>udy on the Transdermal Permeability of Insulin in Vitro[J];International Medicine & Health Guidance News;2004-16
10 XIAO Li-e1,WU Ping-jiang2,WEI Ping2,WU Da-zhang1,2(1.Chongqing Taiji Group Fuling pharmaceutical Factory Co.,Ltd.,Fuling 408000,China;2.Chengdu University of TCM,Chengdu 610072,China);Study on Preparing technique of Baicalin liposomes[J];Strait Pharmaceutical Journal;2010-02
China Proceedings of conference Full-text Database 1 Hits
1 DONG Di,LIU Hong-Mei,SONG Xiao-Dan, ,DU Xia ,WU Lin-Hua* (Derpartment of Pharmcy,the second Affiliated Hospital of Harbin Medical University,Harbin 150081,China);RP-HPLC Determination of Content and Entrapment Efficiency of Itraconazole in Liposome[A];[C];2006
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Kai Guiqing Yuan Chuanxun Hu Xueqiao Pan Jian(Key Laboratory of Bioprocess of the Ministry of National Education, Hefei University of Technology, Hefei 230009, China);Specificity for Ginkgolide A of HPLC[J];Anhui Chemical Industry;2005-02
2 LIU Dong geng1, GUAN Zhong zhen1*, SONG San tai2, LIU Xiao qing2,FENG Feng yi3, ZHANG Pin3, DONG Mei3, XU Li gong4, YIN Ji liang4, YU Shi ying5, CHEN Yuan5 1. Department of Medical Oncology, Tumor Hospital, Sun Yat sen University of M;A Clinical Study of Xeloda as Second Line Treatment for Patients with Advanced Breast Cancer[J];Chinese Journal of Cancer;2001-12
3 HAN Yi ZHOU Yang ZHAO Yong-fang (College of Life Sciences, Wuhan Uniskrsity 430072);The Purification and the Identification of Lecithin and its Application[J];Amino Acids & Biotic Resources;2001-02
4 SHI Li-ping, WANG Lu-huan, LI Ying-li, et al. (Laboratory of Biochemistry PLA General Hospital, Beijing 100853, China);Comparison in~(125) I-IL-8 Envelopment Ratio of Liposome Made by Different Methods[J];Labeled Immunoassays and Clinical Medicine;2001-03
5 Liu Zhanchuan 1,Yan Shijun 1,Liu Li,Li Tongguang 2 (1\ Dept.of Neurosurgery,The Second Clinical College,NBUMS,Changchun 130041; 2 Dept.of Surgery,Changchun Railway Hospital) 〔;Study on intrachemotherapy of C_6 gliomas in rats with BCNU liposome[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;2000-02
6 FU Jing1,BAO Guo-qiang2,WANG Hua-ning2,MA Qing-jiu2,HE Xian-li2,ZHAO Hua-dong2(1.Department of General Surgery,No.451 Hospital of PLA,Xi'an 710054,China;2.Department of General Surgery,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China);Observation of adriamycin assembly and release in vitro using magnetic thermosensitive liposomes[J];Journal of Jilin University(Medicine Edition);2007-01
7 ZHAO Rong Sheng 1, YAN Bao Xia 1, HOU Xin Pu 2 (1. Department of Pharmacy, Peking University Third Hospital, Beijing 100083, China; 2. Department of Pharmaceutics, Peking University School of Pharmaceutical Sciences);The pharmacokinetic characteristics of amphotericin B liposomes injection compared with market injection in rabbits after intravenous administration[J];Journal of Beijing Medical University;2001-03
8 MU Xiao mei,ZHONG Zhen sheng,YANG Mei,CHEN Huan qin(College of Chemical Engineering,South China University of Technology ,Guangzhou510640,China);Preparation of alpha hydroxy acid-containing liposome used in cosmetic[J];China Surfactant Detergent & Cosmetics;2002-05
9 LIN Qiang~1,HUANG Han-chang~2,HAO Liang-nan~1(1.Bio-chemical Engineering College of Beijing Union University,Beijing 100023,China;2.College of Applied Sciences and Humanities of Beijing Union University,Beijing 100083,China);Preparation of arbutin liposome[J];China Surfactant Detergent & Cosmetics;2007-01
10 LU Minfei CHENG Yongqing Department of Applied Chemistry,Northwestern Polytechnical University,Xi'an 710072; LI Lijun WU Jianjun Hospital Attached,Xi'an Jiaotong University,Xi'an 710003;Progress of Study on Passive Targeting of Drug Delivery System[J];Materials Review;2005-09
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 CHAI Yi-feng*,ZHU Zhen-yu and CHEN Xiao-fei(Department of Pharmaceutical Analysis,School of Pharmacy,Second Military Medical University,Shanghai 200433),Fenxi Shiyanshi,2010,29(9):78~122;Pharmaceutical analysis(I)[J];Chinese Journal of Analysis Laboratory;2010-09
2 HU Bo,ZHOU Yu-bin,YANG Yan,YE Xiao-ling,YUAN Zhong-wen,LI Hai-gang,GUAN Shi-xia(School of Chinese Herbal Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510006,China);Determination and entrapment efficiency of docetaxel liposomes for injection by ultrafiltration-HPLC[J];Journal of Guangdong Pharmaceutical University;2012-02
3 TENG Yue1,2,TIAN Hai-shan1,3,ZHANG Rui1,JIAO Yue1,LI Xiao-kun1,3(1.Engineering Research Center of Bioreactor and Pharmaceutical Development,Ministry of Education, Jilin Agricultural University,Changchun 130118,China;2.College of Life Science,Jilin Agricultural University,Changchun 130118,China;3.Wenzhou Medical College,Wenzhou 325035,China);Preparation of rhaFGF liposomes and evaluation of their physical stability[J];Journal of Jilin University(Medicine Edition);2012-05
4 ZHONG Meng YIN Hua-Feng TENG Yong-Zhen WU Jian-Yong ZHANG Jing-Qing(Medicine Engineering Research Center,Chongqing Key Laboratory of Biochemical & Molecular Pharmacology,Chongqing Medical University,Chongqing 400016,P.R.China);Determination of Entrapment Efficiency of Azithromycin Niosomes by Reverse Dialysis Method[J];Chinese Journal of Spectroscopy Laboratory;2012-05
5 CHEN Shu-hua,ZHAN Shi-ping,ZHANG Jing,CHEN Li(College of Environment and Chemical Engineering,Dalian University,Dalian 116622,China);Experimental Research and Properties Characterization of the Preparation of Glucose Liposome with the Supercritical Reverse Phase Evaporation Method[J];Journal of Dalian University;2012-06
6 HUAGN Yongpeng,ZHONG Hui, CHEN Bo,JIAO Jianlan (Research Institute of Chemical Defense,Beijing 102205,China);Preparation and Material Properties Characterization of Capsaicin Powders[J];China Powder Science and Technology;2012-06
7 ZHANG Zhan WEI Gang FAN BaoMin WANG Dong QIAO Ning(State Key Laboratory of Chemical Resource Engineering,College of Materials Science and Engineering,Beijing University of Chemical Technology,Beijing 100029,China);Preparation and analysis of the inclusion complex of octadecylamine with hydroxylpropyl-β-cyclodextrin[J];Journal of Beijing University of Chemical Technology(Natural Science Edition);2013-04
8 DUAN Lian,YAN Yuan,LIU Yuan,LIU Sijia,LI Guofeng Department of Pharmacy,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Analysis of capsaicin in rat plasma using liquid chromatography-tandem mass spectrometry[J];Journal of Southern Medical University;2013-08
9 ZHANG Cai-yun;YI Jia-ming;YUAN Hui-ling;Department of Pharmacy,Anhui University of Traditional Chinese Medicine;Anhui Province Key Laboratory of Research and Department of Traditional Chinese Medicine;;Progress in pharmacokinetics of curcumin and its dosage forms[J];Anhui Medical and Pharmaceutical Journal;2014-01
10 WANG Hui;ZOU Pei-pei;College of Chemistry and Chemical Engineering,Baoji Univ.Arts &Sci.;;Determination of entrapment efficiency for chrysophanol liposomes[J];Journal of Baoji University of Arts and Sciences(Natural Science Edition);2014-01
China Proceedings of conference Full-text Database 2 Hits
1 YUAN Yue,WANG Mi,PAN Hao,GAO Yang,CHEN Hongdan,PAN Weisan (School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Study on niosome as pH-sensitive drug carrier[A];[C];2010
2 ZHANG Wei-yu;ZHOU Xin-qi;SUN Jing-meng;Changchun University of Chinese Medicine;;Studies on Preparation of Yinnaotongpian[A];[C];2015
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Long Xiaoying,Zhu Xiaoxiong, Liang Chaofeng Department of Pharmaceutics Guangdong Medical and Pharmaceutical College;Preparation of Diclofenac Sodium Controlled Release Tablets[J];;1993-01
2 Deng Yihui,Yu Bin,Li Huangqiu,Gu Xueqiu;Preparation of Adriamycin Liposomes by a pH Gradient Method[J];JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSITY;1997-04
3 LIU Ce-li, LI Ao, ZHAO Xiong-fei , et al. (The Southwest Hospital Third Military Medical University, Chongqing 400038, China);A clinical study of capsaicin drug sheet on preventing and treating hypertrophic scar[J];MODERN REHABILITATION;2000-07
4 Wu Mingguang Wang Jinmao Wu Bin Hong Juduan (Dept. of Chem. Inst. Envmt. Sci.);Studies on the Natural Capsaicin Determination[J];Journal of Xiamen University(Natural Science);1993-06
5 Diao Yuhui, Chen Zhiyi Nanjing Gulou Hospital, 210008;Study on Penetration Diffusion of Diclofenac Sodium Paints[J];Journal of China Pharmaceutical University;1996-09
6 Guo Jianxin, Ping Qineng, Huang Luosheng 1 Department of Pharmaceutics; 1Institute of Chinese Traditional Medicine, China Pharmaceutical University, Nanjing 210038;Studies on Preparation and Deformability of Flexible Nano Liposome Containing Cyclosporine[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;1999-03
7 ZHANG Lei, PING Qi Neng, GUO Jian Xin, LIU Zhe Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009;Preparation of Oral Insulin Nano-liposomes and Its Hypogly-cemic Effect[J];Journal of China Pharmaceutical University;2001-01
8 Guo Jianxin, Hu Yiqiao 1, Zheng Liangyuan and Wang Lijing Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009; 1Department of Biology, Nanjing University, Nanjing 210039;Quantitation of Insulin in Poly D,L lactic Acid (PDLA) Microspheres by RP HPLC[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;1999-01
9 Sui Yin,Liu Boaqing,Xia Dongya (Department of Pharmacy,General Hospital of Shenyang Army,110015);Study on arabinoside liposome lypophilized product[J];CHINESE JOURNAL OF HOSPITAL PHARMACY;1995-11
10 Ma Xiaowei and Liang Wenquan(Department of pharmacy,Zhejiang Medical University);STUDIES ON IN-VITRO PERCUTANEOUSPENETRATION OF SODIUM DICLOFENAC PIGMENT[J];;1995-03
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