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《JOURNAL OF GUANGDONG MIDICAL COLLEGE》 1996-02
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DIFFERENTIATION BETWEEN BENIGNANT AND MALIGNANT HYDROTHORAXES BY DETERMINING SA,CEA AND LDH IN SERUM PLUS PLEURAL FLUID

Su Weiqiang;Zhou Ning;Guo Jielian;et al(Department of Respiratory,The Central Hospital of Zhanjiang)  
In 20 patients with malignant and benignant pleural fluid and 40 heathy subjects as control gnoup, the levels of sialic acid(SA),carcinoembryonic antigen(CEA)and lactate dehydrogenase(LDH)were detected by single reagent colorimetry, ELISA and enzymekinesic method,respectively.The results showed that:(1)the serum level of SA is higher in patients with hydrothoraxes whether benign or malignant than that in the control group; (2)the ratio of pleural fluid to serum CEA(≥1.5),of which the specificity and sensitivity is 95%and 55% respectively, is superior to corresponding ratio of SA or LDH for differenriation between benign and malignant hydrothoraxes.
【CateGory Index】: R730.4
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