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Novel measures based on Jensen-schur for medical image registration

HU Shun-bo1,LIU Chang-chun2,YANG Jin-bao2 (1.Department of Physics,Linyi Normal University,Linyi 276005,China;2.School of Control Science and Engineering,Shandong University,Jinan 250061,China)  
In order to reduce the registration time,improve the convergence ability and perform better in the presence of noise,a novel medical image registration measure is proposed,which is called Jensen-Schur measure.According to the Jensen-Schur measure,three kinds of measures are constructed: Jensen-Schur-alpha、Jensen-Rényi-alpha、Jensen-Schur-w.The characters of three measures,mutual information and normalized mutual information are analyzed and compared by applying them to rigid registration of magnetic resonance(MR)/computed tomography(CT) and MR / positron emission tomography(PET) images.The results show that Jensen-Schur-alpha(alpha=2 or 3) and Jensen-Schur-w measures outperform other measures in the computational speed,convergence performance and noise immunity.A multi-modality medical image registration test is conducted and the good result is obtained.
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