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《Polymer Materials Science & Engineering》 2008-02
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Structure and Cell Compatibility of Biocompatible Polyurethane Scaffolds

WANG Xue-li1,HOU Li2,TAN Jing2,TANG Ke-qin1,XIA He-sheng1,LIU Ting2(1.State Key Lab.of Polymer Materials Engineering,Sichuan University,Polymer Research Institute of Sichuan University,Chengdu 610065,China;2.The Hematology Research Laboratory of West China Hospital,Sichuan University,Chengdu 610041,China)  
Polyurethane scaffolds were prepared via pre-polymerization.The influences of cell opener and foam stabilizer on the structure of scaffold were studied.The results show that as the content of the cell opener increased,the pore diameter becomes larger.While the content of the stabilizer increased the proe diameter and the foam density decreases,but the pore volume ratio increases.SEM photos show that the cells of the PU scaffolds are interconnected.Finally the growth of cells can scaffolds was observed.The cells can adhere and secrete extra-cellular matrix and grow on PU three-dimensional scaffolds.The PU scaffolds have good cell compatibility.
【Fund】: 教育部新世纪优秀人才资助计划(NCET-07-0583);; 四川省杰出青年学科带头人培养计划(06ZQ026-032)资助
【CateGory Index】: R318.08
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