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《CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY》 1997-03
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VARIATION OF NITRIC OXIDE SYNTHASE POSITIVE NEURONS IN ISCHEMIC RETINA OF RAT

Ma Ningfang, Yang Shuzhen (Division neuroscience Department of Histology and Embryology, Sun Yat-Sen University of Medical Science, Guangzhou 510089)  
The distribution and variation of Nitric oxide synthase (NOS) positive neurons in the ischemic retina of the SD rats were studied with β NADPH diphorase histochemistry method. The experimental animals were divided into 4 groups according to different ischemic time namely 10, 15, 30 and 60 min. The NOS positive cells were counted and analysed. The result showed the distribution of NOS positive cells were the same either in normal or in ischemic retina. The somata of NOS positive neurons were located in the inner nuclear layer (INL) and the ganglion cells layer (GCL). The average density of NOS positive cells in central area is higher than that of peripheral area but there is no difference in each quadrant of retina. After 15 min of ischemic treatment the NOS positive cells decreased and become more clearly along with ischemic time prolonged. The variation was more obvious in central area than that of peripheral area. Our study indicated that the variation of neurobiology may occur in the retina after 15 min ischemia. The central area of the retina is more sensitivity than that of peripheral area.
【Fund】: 国家自然科学基金
【CateGory Index】: Q954.62
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【References】
Chinese Journal Full-text Database 3 Hits
1 Ma Ningfang Lin Shubin Li Jinxing Li Xiaobing (Department of Histology and Embryology of Guangzhou Medical College, Guangzhou 510182 China);EXPRESSION OF C-FOS FOLLOWING TRANSIENT RETINAL ISCHEMIA IN THE RAT[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;2000-01
2 Pan Aihua, Liu Qiuli, Liu Zhonghao (Department of Neurobiology, Hunan Medical University, ChangSha 410078, China);THE EFFECT OF VERAPAMIL ON THE NOS POSITIVE NEURONS OF POST-ISCHEMIA IN RETINA OF RATS[J];Chinese Journal of Histochemistry and Cytochemistry;2000-04
3 LI Jin-xing1 ,JI Qiong-mei2, MA Ning-fang1 ,LIN Shu-bin1 ,HE Qing-hua1(1. Department of Histology and Embryology ;2. Department of Biochemistry,Guangzhou Medical College, Guangzhou ,510182);Effect of Tetramethylpyrazine on Apoptosis of Retinal Cells after Retinal Ischemia in Rats[J];Academic Journal of Guangzhou Medical College;2002-01
【Co-references】
Chinese Journal Full-text Database 4 Hits
1 Luo Pifu, Xie Yao, Yao Zhibin, Chen Yici, Kuang Guobi (Department of Anatomy, Sun Yat-sen University of Medical Sciences, Guangzhou );EXPRESSION OF c-fos PROTOONCOGENE PROTEIN (FOS) IN THE RAT BRAIN INDUCED BY TRANSIENT GLOBAL CEREBRAL ISCHEMIA[J];Chinese Journal of Neuroanatomy;1993-01
2 Ma Ningfang; Yang Shuzheng(Division of Neuroscience, Department of Histology and Embryology,Sun Yat-Sen University of Medical Science, Guangzhou 510089);VARIATIONS OF THE PARVALBUMIN IMMUNOREACTIVE NEURONS IN ISCHEMIC RETINA OF RAT[J];CHINESE JOURNAL OF NEUROANATOMY;1997-01
3 Zhou Li, Zhang Kanglan, Fang Yiqun. Department of Ophthalmology, Jinan Command General Hospital of PLA, Jinan 250031;Effect of ischemia reperfusion on membrane structure and function in rat retina[J];CHINESE JOURNAL OF OPHTHALMOLOGY;1998-02
4 Wang Yuliang Ba Yankun Central Laboratory,Shanxi Institute of TCM,Taiyuan;Pharmacodynamic and Eiectrophysiological Studies of Ligustrazini on Cardiovascular Tissues—A New Calcium Antagonist?[J];;1985-05
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 NIU Qiang~1,ZHU You-hua~(1*),YU Chang-hu~1,LUO Ming~1,MIAO Ming-yong~2(1.Organ Transplantation Institute of PLA,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;2.Department of Biochemistry and Molecular Biology,College of Basic Medical Sciences,Second Military Medical University,Shanghai 200433);Influence of a self-designed multiple organ preservation solution on apoptosis of renal cortical cells during hypothermic storage[J];Academic Journal of Second Military Medical University;2006-10
2 Wei Shen, Han-Yu Li, Ting-Hua Wang, Wen-Sheng Li. Department of Oph- thalmology, the First Affiliated Hospital, Kunming Medical College, Kunming 650032, Yunnan Province, CAina; Institute of Neurology, Kunming Medical College, Kunming 650031, Yunnan Province, CAina ; Department of Ophthalmology, the Second Affiliated Hospital to Kunming Medical College, Kunming 650101, Yunnan Province, China;Retinal injury and c-fos gene expression[J];International Journal of Ophthalmology;2003-02
3 Wen-Hua Li1, Yong-Sheng Yang2, Hai-Yan Li1, Tao Ma1 1Shanxi Eye Hospital, Taiyuan 030002, Shanxi Province, China;2Eye Hospital, China Academy of Chinese Medical Science, Beijing 100040, China;Pigment epithelium derived factor as a neuroprotective agent against Ischemic-reperfusion induced retinal gonglion cell injury[J];International Journal of Ophthalmology;2007-01
4 Liu Xin, Qiu Xiaohua, Chen Meixia et al. First Clinical Academy of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022;Effect of Tertram ethylpyrazine on macrophages of rat treated with LPS and mechnism analysis.[J];Central China Medical Journal;2006-02
5 WU Yini,HAO Jin.Eye Hospital of China Academy of Chinese Medical Sciences,Beijing 100040,China;The mechanism and clinical application of Ligustrazine on the effect of retinal protection[J];China Journal of Chinese Ophthalmology;2012-01
6 Pan Aihua,Liu Quili,Liu zhonghao Deparment of Neurobiology,Zhongnan Medical University.Changsha,410078;INVESTIGATEION OF VERAPAMIL ON Glu-IR NEURONS OF THE ISCHEMIA-REPERFUSION RETINA OF RAT[J];China Journal of Modern Medicine;2001-02
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