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《International Journal of Ophthalmology》 2010-09
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Influence and mechanism of He-Ne laser on scar formation of filtration canal after trabeculectomy in rabbit

Rui-Lin Wang,Gui-Gang Li,Zhi-Qi Chen,Yan Xiang,Hong Zhang Department of Ophthalmology,the Affialted Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China  
AIM:To investigate the influence of He-Ne laser on connective tissue growth factor (CTGF) expression and collagen formation of fibroblast in filtration site after trabeculectomy in rabbit,and to discuss the mechanism for preventing scar formation with He-Ne laser in vivo. ·METHODS:The upper nasal limbus area next to the upper rectus muscle in right eyes received 10 minutes He-Ne laser irradiation (200mW/cm2) every day for three days,the left eyes served as control. Twenty-four hours after the last irradiation,both eyes of the rabbits were took trabeculectomy surgery. The expressions of CTGF in the filtration area were tested on the 7th,14th and 28th day after surgery and collagen density was tested on the 14th and 28th day after surgery. Each of the time point had 7 rabbits. ·RESULTS:The expression of CTGF was lower than that of the control group's on the 7th and 14th day after trabeculectomy surgery (P=0.01,P=0.005). When examined on the 14th and 28th day,the collagen density of irradiation group were significantly lower than that of the control group's (P=0.013,P=0.01). ·CONCLUSION:Pretreating the filtration area with 200mW/cm2 He-Ne laser may be helpful in preventing scar formation after trabeculectomy in rabbit,possibly due to downregulation of the expression of CTGF and collagen synthesis in fibroblasts. He-Ne laser may be developed into a new scar preventing method in filtration surgery.
【Fund】: New Technology and New Business Foundation in 2008 Affiliated Tongji Hospital Tongji Medical College of Huazhong University of Science and Technology China (No.2008006);; Key Science and Technology Programme of Wuhan City Hubei Province China ( No.200852199600)~~
【CateGory Index】: R779.6
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【Citations】
Chinese Journal Full-text Database 6 Hits
1 SHU Bin, HAO Lin lin, DAI Jia ping, WU Zong yao (Department of Physical Medicine and Rehabilitation, Daping Hospital, Third Military Medical University, Chongqing 400042, China);Inhibitory effects of He Ne laser repeated irradiation on collagen synthesis in hypertrophic scar-derived fibroblasts in culture[J];Acta Academiae Medicine Militaris Tertiae;2000-11
2 SHU Bin,HAO Lin lin,WU Zong yao,et al.Daping Hospital,Third Military Medical University,Chongqing 400042,China;Effects of He-Ne laser with various energy densities on the growth of cultured fibroblasts in hypertrophic scar[J];Modern Rehabilitation;2002-16
3 WANG Da-Bo, JI Shu-Xing, WANG Jing-Hua From the Department of Ophthalmology, the Affiliated Hospital of Medical College of Qingdao University, Qingdao 266003, Shandong Province, China;Experimental study of anti-proliferative effects of mitomycin C[J];Recent Advances In Ophthalmology;2002-02
4 LI Cheng,LI Ying-xin(Biomedical Engineering Department,Tianjin Medical University,Tianjin 300070,China);Effect of low-level laser biostimulation in wound healing[J];Chinese Medical Equipment Journal;2007-10
5 LIU Yong-ying,YANG Ji-qing,XIANG Zhen.The Institute of Biomedical Engineering, The Fourth Military Medical University, Xi'an 710032, Shaanxi, China;Effect of Low-level Laser Irradiation on Organism(review)[J];Chinese Journal of Rehabilitation Theory and Practice;2006-07
6 WEI Ping~ # ,WANG Ai-qin ,Lei Xun-wen* ,CAO Zhi-xin** ,LI Xiao-lin,WANG Qin (Department of Ophthalmology,the First People's Hospital of Lanzhou City,Lanzhou 730050,China Research and Development Centre for Ecomaterials of Lanzhou,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou730000,Department of Ophthalmology,Clinical Medical College,Lanzhou University,Lanzhou730000Department of Pathology,the First Peoples Hospital of Lanzhou City,Lanzhou730050);Effects of Butyrylchitosan on Expression of Proliferating Cell Nuclear Antigen in Fibroblast Proliferation of Rabbit Eyes after Filtering Operation[J];Acta Academiae Medicinae Sinicae;2006-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HAO Lin-lin,SHU Bin,WU Zong-yao,et al. (Department of Physical Medicine and Rehabilitation,Daping Hospital,the Third Military Medical Universtiy,Chongqing 400042);Selectively inhibitor effects of pulsed Nd∶YAG laser on collagen synthesis of cultured fibroblasts of hypertrophic scar[J];Chongqing Medical Journal;2001-04
2 XIA Lei,LUO Zhuo-Jing,WANG Zhe Institute of Orthopedics,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China;Effect of low power laser irradiation on glial scars following spinal cord injury[J];Journal of the Fourth Military Medical University;2009-18
3 Feng Qiao,Jin-Hua Liu Department of Ophthalmology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Study on the dosage,opportunity and frequency of injecting 5-Fu under conjunctiva after glaucoma filtering surgery[J];International Journal of Ophthalmology;2008-03
4 Jun Hu~1,Gui-Gang Li~1,Hong Zhang~1,Nan Xiang~1,Zhi-Qi Chen~1,Rui-Lin Wang~1, Yan Xiang~1,Bin Li~1,Zheng-Jia Li~2,Yan-Yan He~2,Li-Fang Wang~2 1 Department of Ophthalmology,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430030,Hubei Province,China 2 Wuhan National Laboratory for Optoelectronics,Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China;The influence of He-Ne laser on scar formation after trabeculectomy in rabbits[J];国际眼科杂志(英文版);2010-02
5 Pan Zhenhua~1 Li Yingxin~1 Wang Xing~2 Chen Hongli~1 Xiao Quanzhi~1 (1 Laser Medicine Laboratory,Biomedical Engineering Department,Tianjin Medical University,Tianjin 300070,China 2 Stomatological Hospital of Tianjin Medical University,Tianjin 300070,China);Effects of Low-Level Laser Therapy on Cutaneous Wound Healings with Three Doses[J];Chinese Journal of Lasers;2010-02
6 XU Yu,SHENG Cheng-yi,ZHU Jian-ping,LI Rui-ming (Medical School of Huzhou Teachers College,Huzhou 313000,Zhejiang,China);Frostbite Research Progress[J];Journal of Liaoning University of Traditional Chinese Medicine;2010-08
7 Zhang Shun qing,Wu Ai qun,Zhang Wei hong,Yue Xin can,Zeng Guang wei Zhang Shun qing,Zhang Wei hong,Yue Xin can,Zeng Guang wei, Department of H uman Anatomy, Basic Medical College,Zhengzhuo University, Zhengzhou 450052, Hena n Province, China Wu Ai qun,Department of Human Anatomy, Second Military Medical University of Chinese PLA, Shanghai 200433, China;Influence of He-Ne laser irrigation on the growth and development of neurons cu ltured in vitro[J];Chinese Journal of Clinical Rehabilitation;2005-01
8 Shu Bin,Yu He ping,Yu Zi qin,Fang Xiang qin,Ma Xiao lin,Wu Zong yao Shu Bin,Fang Xiang qin,Department of Rehabilitation Medicine,Daping Hospital, Third Military Medical University of Chinese PLA,Chongqing 400042,China Yu He ping,Department of Rehabilitation Medicine,First Affiliated Hospital,Ch ongqing University of Medical Sciences,Chongqing 400041,China Yu Zi qin,Chongqing Health Prosthesis &Orthosis Co.,Ltd.,Chongqing 400042,Ch ina Ma Xiao lin,War and Trauma Center of Chinese PLA,Daping Hospital,Third Milita ry Medical University of Chinese PLA,Chongqing 400042,China Wu Zong yao,Department of Rehabilitation Medicine and Physiotherapy,Southwest Hospital,Third Military Medical University of Chinese PLA,Chongqing 400038,Chin a;Apoptosis of cultured fibroblasts derived from scar induced by He Ne laser[J];Chinese Journal of Clinical Rehabilitation;2005-02
9 Pan Zhen-hua1,Wang Xing2,Li Cheng1,Li Ying-xin11Tianjin Medical University,Tianjin 300070,China;2Stomatological Hospital of Tianjin Medical University,Tianjin 300070,China;Effects of low-intensity laser irradiation at 630 and 808 nm on rat cutaneous wound healings[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2008-52
10 LI Dan, LIU Bing, LIN Jun Jun, RU Hai Xia, ZHANG MeiFrom the Department of Ophthalmology, the Air Force General Hospital, Beijing 100036,China;Experimental study of adjunctive mitomycin C on glaucoma filtration surgery[J];Recent Advances In Ophthalmology;2003-03
China Proceedings of conference Full-text Database 1 Hits
1 ;MRI检测常见问题探讨[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LUO Xiao sen 1, NI Xiao wu 2, LU Jian 2, HE An zhi 2, LIU Xiao ran 2, XU Jiang ying 1, SHEN Jian 1 (1.Nanjing Military Medical college,Second Military Medical University,Nanjing 210099,China; 2.Department of Applied Physics,Nanjing University;Influence of He-Ne Laser on Oxygen Dissociation of Erythrocyte[J];Journal of Optoelectronics.laser;2002-04
2 ZHANG Canbang1,2, ZHOU Lingyun1, LIU Shuxiao3, WU Guangmin1, DUAN Lianghe1 (1.Research Center of Nonlinear Science,Kunming University of Science and Technology,Kunming 650093,China; 2.Department of Physics,Mengzi Teacher′s College,Mengzi 661100,China; 3.Department of Neurology,Kunming General Hospital of Chendu Military Command,Kunming 650032,China);Explaination on Intra-vascular Laser Irradiation Decreasing Consistency of Fibrinogen of Blood[J];Journal of Optoelectronics.laser;2003-10
3 朱明华;Studies on the Cell Separation of the Secondary Xylem of the Outgrowth of the Peach and Apple[J];Foreign Medical Sciences Biomedical Engineering;1995-03
4 WU Qiang (Orthopaedic department,Union Hospital,Wu Han 430022,China);The application of chitosan in cartilage tissue engineering[J];Foreign Medical Sciences Biomedical Engineering;2002-02
5 He Qingli 1,2 ,Xu Yanliang 2,Xu Rong 2,Zhang Zhenxi 1 1 Biomedical Engineering Institute of Xi′an Jiaotong University,Xi′an 710049 2 Physics Department of Northwest University,Xi′an 710069;The Mechanism Analysis of Blood Protein Activity Adjusted by Low Level Laser[J];Acta Photonica Sinica;2003-06
6 Ma Ning Wang Qin Sun Shengling Wang Aiqin  (Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China);Progress in Chemical Modification of Chitin and Chitosan[J];Progress In Chemistry;2004-04
7 CHEN Min 1,2 ,LUO Qing-ming 1 (1.Insitute of Biomedical Photonics,Huazhong University of Science and Technology; 2.Department of internal medicine,Hospital of Huazhong University of Science and Technology,Wuhan 430074,Hubei,China);Biologic Effect of Low Level Laser and its Improving Action on Red Blood Cell Deformability[J];Acta Laser Biology Sinica;2002-01
8 YANG Zai fu 1, YANG Jing geng 1, GAO Guang huang 1, HU Zheng rong 2, CHEN Hong xia 1,QIAN Huan wen 1(1. Institute of Radiation Medicine, Beijing 100850, China ;2. Department of Electronic Engineering Southeast University, Nanjing 210096;Mechanism on Bio-effects of Low Intensity Laser Radiation[J];Acta Laser Biology Sinica;2002-05
9 HE Qing-li 1,2 ,HE Jian 2,ZHANG Zhen-xi 1 1.The Key Laboratory of Biomedical Information Engineering of Ministry of Education,and Biomedical Engineering Institute,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,China 2.Physics Department of Northwest University,Xi'an 710069,China;A physics model of biology enzyme activity rising by low level laser[J];Laser Journal;2004-04
10 LI Jie 1, HUAN Chun-yan 2, LI Xiao-ling 3,HU Ping 2, YANG Bing-jian 3(1. Department of opthalmology,Beijin Corps Hospital,CHINESE PEOPLE'S Armed Police Forces,Beijing 100027,China;2. Department of chemical industry,Tsinghua University, Beijing 100084,China; 3.Department of opthalmology, PLA Genertal Hospital,Beijing 100853,China );Chitosan membrane on nonpenetrating filtering in rabbits[J];Academic Journal of Pla Postgraduate Medical School;2005-01
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