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《International Journal of Ophthalmology》 2010-09
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Analysis of the effect on mitomycin C combined with autologous limbal stem cell in treatment of recurrent pterygium

Yu-Ling Wei Department of Ophthalmology,the Fourth People's Hospital of Liuzhou,Liuzhou 545001,Guangxi Zhuang Autonomous Region,China  
AIM:To explore the outcome of mitomycin C combined with autologous limbal stem cell transplantation for treatment of recurrent pterygium. ·METHODS:Totally 69 cases 87 eyes with recurrent pterygium were randomly divided into two groups. The treatment group:35 cases 45 eyes after pterygium exci-sion were treated with mitomycin C combined with autologous limbal stem cell transplantation. The control group:34 cases 42 eyes after pterygium excision were treated with autologous limbal stem cell transplantation. ·RESULTS:During a follow-up of 3 to 12 months,in the treatment group 44 eyes were cured and the cure rate was 98%; with 1 eye of recurrence,the recurrence rate was 2%; in the control group,36 eyes were cured and the cure rate was 86%; with 6 eyes of recurrence,the recurrence rate was 14%. Recurrence rate of the two groups was statisti-cally significant (χ2 = 4.273,P=0.039). ·CONCLUSION:Mitomycin C combined with autologous limbal stem cell transplantation significantly increases the cure rate and reduces the recurrent rate,worthy of promotion in clinical therapy.
【CateGory Index】: R779.6
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 Xiao-Xia Zhao1,Li-Li Wang2 1 China-Cuba Friendship Eye Hospital,Xining 810000,Qinghai Province,China;2 Department of Ophthalmology,the Fourth Hospital of Xi'an City,Xi'an 710004,Shaanxi Province,China;Effect of autograft with limbal stem cell transplantation on the surgical treatment of pterygium[J];International Journal of Ophthalmology;2008-04
2 Kui-Xiang Liu,Gui-Qiu Zhao,Qing-Lan Kong,Jing Lin Department of Ophthalmology,the Affiliated Hospital of Medical College of Qingdao University,Qingdao 266003,Shandong Province,China;Comprehensive analysis and therapy of recurrent pterygium[J];International Journal of Ophthalmology;2008-11
3 Yu-Shun Xue,Rui Shi,Yu-Qin Li Deaprtment of Ophthalmology,Shaanxi Provincial People's Hospital,Xi’an 710068,Shaanxi Province,China;Comparison of three methods for pterygium treatment[J];International Journal of Ophthalmology;2009-09
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 Kui-Xiang Liu,Gui-Qiu Zhao,Qing-Lan Kong,Jing Lin Department of Ophthalmology,the Affiliated Hospital of Medical College of Qingdao University,Qingdao 266003,Shandong Province,China;Comprehensive analysis and therapy of recurrent pterygium[J];International Journal of Ophthalmology;2008-11
2 Jing Lu,Fu-Rong Liu Chengdu Aier Eye Hospital,Chengdu 610041,Sichuan Province,China;Curative effect review of 33 eyes of recurrent pterygium surgery[J];International Journal of Ophthalmology;2010-03
3 Xiao-Yu Zhu Department of Ophthalmology,Yangzhou No.1 People's Hospital,Yangzhou 225001,Jiangsu Province,China;Clinical observation of primary pterygium treated by reverse stripping[J];International Journal of Ophthalmology;2011-09
4 HU Xiao-yun.General Hospital of Tongling Nonferrous Workers,Tongling 24400,China;Efficacy of two methods of autograft conjunctival transplantation for pterygium[J];Journal of Clinical Ophthalmology;2011-03
5 WEIXiu-hua,SUJin-liang,SUKe-xin,etal.(Ophthalmology Department,Daqing people's Hospital,Daqing 163316);Observation on Effect of Two Kinds of Operation in Treatment of Initial Pterygium[J];Chinese Journal of Trauma and Disability Medicine;2011-07
【Secondary Citations】
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1 Quan-Chen Xiong,Yu-Ping Zheng Department of Ophthalmology,the Second Affiliated Hospital of Xi'an Jiaotong Un iversity,Xi'an 710004,Shaanxi Province,China;Cornesocleral limbus autotransplantation with fresh amnion for recurrent pterygium[J];International Journal of Ophthalmology;2004-06
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3 Xiao-Xia Zhao1,Li-Li Wang2 1 China-Cuba Friendship Eye Hospital,Xining 810000,Qinghai Province,China;2 Department of Ophthalmology,the Fourth Hospital of Xi'an City,Xi'an 710004,Shaanxi Province,China;Effect of autograft with limbal stem cell transplantation on the surgical treatment of pterygium[J];International Journal of Ophthalmology;2008-04
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5 CHEN Guang-yue.Department of Ophthalmology,The Second Hospital of Sanming City,Fujian 366000,China;Treatment of pterygium with corneal limbal autograft transplantation in 60 cases[J];Chinese Journal of Ocular Trauma and Occupational Eye Disease(With Ophthalmic Surgery);2006-04
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