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《International Journal of Ophthalmology》 2011-09
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Advances on p38 signal transduction pathway and corneal neovascularization

Hai-Feng Zhang,Yan-Yan Zhong,Xiao-He Lu Department of Ophthalmology,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,Guangdong Province,China  
Inflammation can promote the growth of corneal neovascularization.p38 mitogen-activated protein kinase signal transduction pathway may play an important role in the progress of inflammation by controlling the expressions of IL-1β,IL-6,TNF-α and so on.p38 inhibitors not only suppress the expressions of inflammatory mediators,but also block their activities.p38 inhibitors greatly curb the progress of inflammations.It is a new strategy to explore the developing mechanism of corneal neovascularization through the pathway of p38 signal transduction.
【Fund】: 中国广东省科技计划项目资助(No.2008B080703037)~~
【CateGory Index】: R779.65
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