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《International Eye Science》 2013-09
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Sliding transplantation of auto-corneal limbus stem cell combined with mitomycin C for pterygium treatment

Fu-Lu Zhong, Xue-Xi Li, Wei-Jie He Department of Ophthalmology, the 180th Hospital of Chinese PLA, Quanzhou 362000, Fujian Province, China  
AIM: To evaluate the efficacy of sliding transplantation of auto-corneal limbus stem cell combined with mitomycin℃(MMC) on pterygium treatment. METHODS: Totally, 79 patients (89 eyes) who received treatment at our hospital were selected. Eighty-nine eyes of 79 patients with pterygium were randomly divided into two groups: 40 patients (45 eyes) in group A underwent sliding limbal autograft transplantation with MMC and 39 patients (44 eyes) in group B underwent simple limbal autograft transplantation. Recurrence rate and complications were observed during the 12-month follow-up. RESULTS: One of 45 eyes (2%) of group A and six of 44 eyes (14%) in group B were recurrent with significant difference (P0.05). One eye with corneal epithelium damage was observed in group A, it was healed with treatment after 5 days. Photaesthesia, lachrymation and pain were relevantly severe in 4 eyes, and 3 eyes displayed delayed union in conjunctival wounds (12-15 days). In B group, 3 eyes slight edema of grafts, 1 eye was growth of a wound granulation, and 1 eye was relevantly severe in photaesthesia, lachrymation and pain. Complications compared two groups had no significant difference (P0.05). CONCLUSION: Sliding transplantation of auto-corneal limbus stem cell combined with MMC for pterygium had advantages of lower recurrence rate, rapid recovery and less complications.
【CateGory Index】: R779.6
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