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《International Medicine & Health Guidance News》 2005-20
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To Investigate the antibiotic resistance of Xanthomonas maltophilia in Guangzhou during 2000~2003

LI Hongyu PAN Kunyi WU Xiquan ZhONG Rihui Department of Laboratory Medical, The Second Affiliated Hospital, SUN YAT-SEN University, Guangdong Zhuangzhou 510120, China  
Objective To investigate the antibiotic resistance of Xanthomonas maltophilia(Xan) in Guangzhou during 2000~2003. Method The strains were isolated and cultured by routine methods, identified by API, To made antimicrobial susceptibility test(AST) by K-B. The data statistics by WHONET 5 and SPSS. Result The rates of resistance to 11 antibiotics which are common. use in clinical treatment respectively were Sulfamethoxazole-Trimethoprin25.4%~38.4%,Ticarcillin/clavulanic acid 40.3%~69.7%,Ceftazidime41.8%~61. 8%,Cefoperazone/Sulbactam 40.3%~56.6%, Ciproflozacin40.3%~69.7%,Cefepime68.6%~82.9%,Piperacillin/ Tazobactan68.6%~85.5%,Amikacin79.1%~97.0%,Cefoperazone88.7%~91.0%,Piperacillin88.6%~100.0%andAztreonam89. 5%~95.5%.In the four years, the differences of resistance of Xan to Piperacillin, Cefepime ,Sulfamethoxazole- Trimethoprin and Cefoperazone significant(P0.05),and those are are no significant (p0.05). Conclusion SXT、TCC and CAZ are the valid antibiotics to Xanthomonas maltophilia.
【Fund】: 广州市科委科研重点项目(2000-z-027-01-02-3
【CateGory Index】: R446.5
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