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《Acta Medicinae Sinica》 2006-03
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Study on antiviral activity of rhubarb anthraquinone analogues to influenza virus

LIANG Rong-gan,LUO Wei-sheng,LI Li-ya,et al.∥Guilin Medical College,Guilin 541004,China  
Objective:To evaluate the anti-influenza virus effect of Rhubarb Anthraquinone Analogues in cell culture.Methods: By the method of cell culture and using Ribavirin as a positive control,the cytopathic effect(CPE) was observed.Results: The TC_(50) and IC_(50) of the Rhubarb Anthraquinone Analogues were 226.1μg/ml and 122.4μg/ml,respectively.The TI was 1.9.Moreover,Rhubarb Anthraquinone Analogues also showed a dose-dependent response in inhibiting influenza virus.Conclusion: Rhubarb Anthraquinone Analogues can inhibit influenza virus in MDCK cell.
【Fund】: 广西科学研究与技术开发计划项目(桂科攻0332006)
【CateGory Index】: R285.5
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