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《Acta Medicinae Sinica》 2008-01
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Clinical study on treatment of acute cardiogenic pulmonary edema by noninvasive mechanical ventilation

ZHANG Yu-mei The Fifth Hospital of Guilin City,Guilin 541004,China  
Objective:To estimate the efficacy of non-invasive positive pressure ventilation(NIPPV)in the treatment of the patients with acute cardiogenic pulmonary edema(ACPE).Methods:60 patients were randomly assigned to receive conventional oxygen therapy or NMV supplied by a standard ventilator through a face mask,with noninvasives mechanical ventilation in the treatment.Blood gas and vital signs were obtained forehead.Results:Endotracheal intubation was required in 5 of 30 patients assigned to receive NMV and in 12 of 29 assigned to receive conventional oxygen therapy.Resolution time was significantly shorter in the NMV group median40(5~77)vs 145(49~263)min(P0.01),NMV led to a rapid improvement in oxygenation in the first 2h.There were no differences in hospital and ICU length of stay or mortality.Conclusion:In this study of acute cardiogenic pulmonary edema,NMV is superior to conventional oxygen therapy.It can be recommended for clinical use.
【CateGory Index】: R541.6
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