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《Acta Medicinae Sinica》 2010-02
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Clinical characteristics and antibiotic resistance of infections of staphylococcus aureus in children

WANG Qun,GAO Yan,OU Wei-lin,et al.Department of Pediatrics,The Affiliated Hospital of Guilin Medical University,Guilin 541001,China  
Objective: To investigate the clinical characteristic and antibiotic resistance of Staphylococcus aureus(SAU)from children who got infections,and provide information for clinic.Methods:The total children infected with SAU were investigated by us in the Affiliated Hospital of Guilin Medical University. VITEK32 automatic microbial monitor GPS was used to test the antimicrobial sensitivities of SAU isolates to 20 kinds of drugs.Results: 42 strains of SAU were separated.The most common locus where SAU was positive was liquor puris and secretion.The most common age with SAU infection was 0~3,which accounted 66.67%.The resistance rates to penicillin,erythromycin,clindamycin,tetracycline and oxacillin were 100.0%,76.2%,66.7%,66.7%,47.6%,respectively and the sensitive rates to cefazolin,cefuroxime,cefotaxime,ceftizoxime, sulfamethoxazole/trimethoprim and norfloxacin exceeded 85.0%.No strain was found resistant to levofloxacin,minocycline,vancomycin,teicoplanin,rifampicin,fusidic acid,furadantin and dalfopristin.Conclusion: Among samples of liquor puris and secretion,the proportion of SAU separation from skin and soft tissue infections and infants was comparatively large.The resistance rates to penicillin,erythrocin and clindamycin were high in our findings.Most of the β-lactam antibiotics,sulfamethoxazole/trimethoprim,fusidic acid and furadantin were still suitable for SAU infections in children in Guilin.
【Fund】: 广西壮族自治区卫生厅科研课题资助项目(Z2009055)
【CateGory Index】: R446.5
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