Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《ACTA MEDICINAE SINICA》 1998-02
Add to Favorite Get Latest Update

Study on the Changes in Plasma Fibronectin Level of Poisoned Patients Following Agkistrodon acutus Bite

Liu Taowen,Cao Minghua,Wen Shangwu//Institute of Bioengineering,Guilin Medical College(541004)  
To illustrate the possible role of plasma fibronectin(Fn) changes in patients with Agkistrodon acutus venom(AAV)envenomation,agar rocket electrophoresis assay was conducted for the the plasma Fn concentration of eight patiens with disseminated intravascular coagulationlike syndrome(DIClike syndrome) following Agkistrodon acutus bite at pretreatment and 12 control persons were measured similarly.It was found that the plasma Fn levels in poisoned group and control were (287.7±65.6)mg/L(±s) and (264.3±37.9)mg/L(±s),respectively.The difference in plasma Fn concentrations between patients and control was not statistically significant (P0.05).The results indicated that Fn,as a substrate of coagulation factor  (Fa),was not involved with the intravascular microclot which noncrossing fibrin forms due to absence of Fa in coagulation abnormalities caused by AAV posisoning.It is concluded that the plasma Fn in normal range supports the evidence of DIClike syndrome induced by AAV envenomation without existing thrombin.
【Fund】: 国家自然科学基金
【CateGory Index】: R446.112,R646
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Xiao Changhua, He Lifeng, Tan Shaozong, Yang Junru, Dong Fuming (Kunming Institute of Zoology, Acadmia Sinica);STUDIES ON THE THROMBIN-LIKE PRINCIPLES OF AGKISTRODON ACUTUS VENOM Ⅰ. ISOLATION AND PURIFICATION OF ITS IDENTIFICATION OF PHYSICAL AND CHEMICAL PROPERTY[J];动物学研究;1988-S1
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 ZHENG Ying, SHEN Ju-ren, QIU Wei, ZHANG Fu-qiang, ZHOU Wei-guo, FAN Quan-shui (The Military Medical Institute of Cheng-Du Military Area CDC, Kunming 650032,China);Purification Process of 38ku Thrombin-Like Enzyme from Agkistrodon acutus Venom[J];药物生物技术;2009-01
2 Luo Xiaoqing1,2,Yang Huaxin3 and Jin Shaohong3(1China Pharmaceutical University,Nanjing 210009;2Suzhou Health College of Technology;3National Institute for the Control of Pharmaceutical and Biological Products);Study Advances of Defibrase[J];中国药事;2008-11
3 ZHENG Ying, XIANG Zuo Yun YAO Guang Ning,WANG Wei Xiang,YANG Mei Feng (Institute Military Medicine,Kunming,650032,China);Purification of Arginine-esterase from Agkistrodon acutus Snake Venom[J];蛇志;2003-01
4 He Guozhen, Zheng Lijun, Yao Yong, Tang Liyun 1 (Guangdong Yantang Biochemistry Pharmaceutical Co. Ltd, Guangzhou 510507; 1Biotechnology College, South China Agriculture University, Guangzhou 510642));Purification of Defibrase with Affinity Chromatography[J];药物生物技术;1998-04
5 Liu Taowen,Cao Minghua,Wen Shangwu//Institute of Bioengineering,Guilin Medical College(541004);Study on the Changes in Plasma Fibronectin Level of Poisoned Patients Following Agkistrodon acutus Bite[J];华夏医学;1998-02
6 He Lifeng Xiao Changhua Dong Fuming Yang Lianxi (Kunming Institute of Zoology, Academia Sinica);STUDIES ON THE THROMBIN-LIKE PRINCIPLES OF Agkistrodon acutus VENOM III. STUDIES ON HEMOSTATIC EFFECT OF HEMOCOAGULASE[J];动物学研究;1990-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Zhang; Hong-ji, Xiao Chang-hua, Tang Shao-zong, Yamg Jun-ru (Kunming Institute of Zoology, Academia Sinica);Study on isolation from the venom of Agkistrodon acutus and its biological activity[J];动物学研究;1980-02
2 Liu Kwang-fen Chiou Shu-yu Lee Bing Department of Pharmacology, Fukien Medical University Tu Guang-chou Kunming Institute of Zoology, Acadetnia Sinica;IDENTIFICATION OF PHYSIOLOGICAL EFFECTS AND ENZYMATIC ACTIVITIES IN THE VENOM OF Agkistrodon acutus (FROM FUKIEN) AFTER FRACTIONATION BY CHROMATOGRAPHY[J];动物学研究;1980-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved