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Effects of clostridium butyricum in adjuvant treatment of patients with irritable bowel syndrome

ZHU Ya-bi,LI Hong-guang, WANG Chang-xiong, WANG Wang-yue (Department of Gastroentrology,People′s Hospital of Lishui,Zhejiang Province,Lishui 323000,China)  
Objective To observe the effects of clostridium butyricum in adjuvant treatment of patients with irritable bowel syndrome(IBS).Methods From february of 2011 to 2012,78 patients with IBS were recruited and were randomly divided into observation group and control group(both n=38).Two groups received food direct and common drugs treatment,and observation group was given clostridium butyricum 500 mg two a day for 4 weeks.The treatment effects were compared.Results In observation group control group,marked improvement and active treatment were seen in 20,14 and 17,17 cases,respectively.The total effective rate in two groups were 94.9 %,79.5%.A significant difference was seen in effective rate between two groups(P0.01),and no significant adverse reactions were seen in either group.Conclusion The adjuvant treatment of IBS with clostridium butyricum is successful and worthy of clinical use.
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