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《Journal of Gannan Medical College》 2003-01
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A Study of Local Anesthetic Effect of Cestrum Nocturnum Water Extract

ZENG Jing,HUANG Xian hua,LAI Fei,YE He yang,ZHU Zun ping,YANG Jin ge (Department of Pharmacology ,Gannan Medical College,Jingxi Ganzhou 341000)  
Objective:To study the local anesthetic effect of Cestrum Nocturnum.Methods:The conventional local anesthetic methods were used:(1)the method of the action potential of isolated sciatic nerve in toads;(2)themethod of infiltration anesthesia in guinea pig;(3)the method of intravertebral anesthesia in rabbits;(4) the method of superficial anesthesia in rabbits.Results:20% Cestrum Nocturnum(CN)can completely inhibit action potential of the isolated sciatic nerve in toads,but less than 1% hydrochloride procaine.It has effect of infiltration anesthesia similar to 1% procaine,and adrenalin hydrochloride can enhance its anesthetic intensity and obviously prolong the time of local anesthesia.It has effect of intravertebral anesthesia similar to 1% procaine too.It has also effect of superficial anesthesia,but less than 1% procaine.Conclusion: CN has local anesthetic effect.
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 6 Hits
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