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《Chinese Journal of Infection Control》 2010-01
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Antimicrobial activity of linezolid and other antimicrobial agents against Enterococci spp. in vitro

WANG Ding-cheng, ZHANG Hui-zhong, YANG Li-hua, GE Wei, SHAO Hai-lian, HAN Xiang-ni (Tangdu Hospital of Fourth Military Medical University, Xi'an 710038,China)  
Objective To evaluate in vitro activity of linezolid and other antimicrobial agents against Enterococci spp. isolated from clinic. Methods Identification and antimicrobial sensitivity test of Enterococci spp. was carried out by Microscan WalkAway-40 system. Results No linezolid-resistant strain was detected in 117 Enterococci spp. strains. Resistant rate of Enterococcus faecium and Enterococcus faecalis against vancomycin was 4. 41 % and 5.71% respectively, the resistant rates to penicillin, ampicillin, erythromycin, high concentration gentamycin, levofloxacin and ciprofloxacin were all above 70%. Conclusion Linezolid has high activity against Enterococci spp. , especially the control of infections caused by multidrug-resistant isolates.
【CateGory Index】: R969.3
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