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《World Clinical Drugs》 2014-10
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Progress of antidepressants in transdermal drug delivery system

LUO Jing;LUO Hua-fei;WANG Hao;National Pharmaceutical Engineering and Research Center, China State Institute of Pharmaceutical Industry;  
Traditional oral administration of antidepressants often has lower bioavailability, high costs and poor patient compliance. Transdermal drug delivery system(TDDS) of antidepressants can greatly improve the efficacy and reduce the adverse drug reactions, which has become a hot research topic. This review describes the pathogenesis of depression disorder, the classifi cation of antidepressants and the application of antidepressants of TDDS.
【Fund】: 国家“重大新药创新”科技重大专项(2014EX09507006-002)
【CateGory Index】: R94
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