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《Journal of International Reproductive Health/Family Planning》 2008-01
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Breast Cancer in Relation to Induced Abortions in a Cohort of 267040 Women in Shanghai

GAO Daoli1, YE Zhan2, QIN Qin2, Ray RM2, Thomas DB2, WANG Wenwan1 1. Zhongshan Hospital Brand, Fudan University , Shanghai 200052,China 2. Fred Hutchinson Cancer Research Center, Seattle, USA  
Objective: Evaluation of the possible influence of induced abortion on breast cancer risk. Methods: The study was in a cohort of 267040 women enrolled in a Randomized Trial of Breast Self-examination in Shanghai. The study consisted of two parts: a cohort study and a case-control study nested within the cohort. Results: Based on answers to a baseline questionnaire, subsequent breast cancer risk was not significantly associated with ever having had an induced abortion. After adjustment for potential confounders, the relative risk estimate was 1.06 ( 95% CI: 0.91~1.25 ), and there was no trend toward a correlation in risk with the number of abortion. Analysis of data from more detailed interviews of 652 cases and 694 controls from the cohort yielded similar results. There was also no overall increase in risk for in women who had an induced abortion for their first birth. A few women had undergone an abortion after 13 weeks of gestation or before their first child. Although an increase in risk was observed in such women, the increase was not statistically significant. Conclusions: Abortions as they have been performed in China are not an importan risk factor of breast cancer.
【CateGory Index】: R737.9;R169.42
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【Co-references】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Ning LUO ZhiMing DENG JieMing Xiashan Maternity and Child Healthcare Hospital of Guangdong, Zhanjiang 524013,Guangdong,China;Research in the Relationship between the Development of Breast Cancer and Correlative Factors in Women[J];International Medicine & Health Guidance News;2006-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 SHI Xi shun, WU Bin, HU Zhi jian, et al. ( Fujian Medical University, Fuzhou,350004 China);A Case-control Study on Risk Factors of Breast Cancer for Women in Fuzhou[J];STRAIL JOURNAL OF PREVENTIVE MEDICINE;2000-05
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