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《International Journal of Internal Medicine》 2008-03
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Efficacy of compound matrine injection plus intensity-modulated radiation treating for nasopharyngeal carcinoma patients

XIE Qiang,ZHAO Dang,LIU Xing-jing,HUANG Zuo-ping,ZOU Bing-xin,Wang Li-gen.Department of Oncology,Guangdong Provincial Corp Hospital,Chinese People's Armed Police Forces,Guangzhou 510507,China;  
Objective To study the efficacy of compound matrine combined injection plus intensity modulated radiation treating for patients with nasopharyngeal carcinoma(NPC).Methods One hundred and thirty six patients with NPC were randomly divided into therapeutic group and control group.The patients in therapeutic group were treated with compound matrine and intensity modulated radiation therapy(IMRT),while the patients in control group were treated with IMRT.Results The standard uptake value(SUV) of primary tumor in therapeutic group was significantly decreased than that in control group after therapy.The side effects of mucosa were fewer in therapeutic group while the infection rate of pharynx oralis was higher in control group.At the same time,the number of immune cells increased in therapeutic group.Conclusion Compound matrine can decrease the side effects of IMRT and improve humoral immunity in NPC patients.
【CateGory Index】: R739.63
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