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《International Journal of Laboratory Medicine》 2006-02
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Role of serum κ/λ ratio detection in multiple myeloma diagnosis

LI Hua,ZHAI Tan.Department of Clinical Laboratory,Donghua Hospital of Zhongshan Medical University,Dongguan,Guangdong 523100,China  
Objective To explore the clinical value of the immune rate nephelometry (IRN)in detecting the rate of serum κ and λ,and diagnosing multiple myeloma.Methods Twenty-five cases of multiple myeloma (MM),28 cases of M protein sickness and 120 cases of healthy people were detected for the rate of serum κ/λ by the Immage Protein Machine the results were analyzed.Results 0.8% of healthy people was positive, the positive rate of κ and λ type M protein sickness were 23.1% and 26.7% respectively, the positive rate of κ and λ type multiple myeloma was 92.3% and 100% respectively. Conclusion The method of IRN has high sensitivity and stability in detecting the light chain of serum κ and λ on/with the Immage Protein Machine.The accuracy value of prognosing MM with the rate of serum κ and λ is better.
【CateGory Index】: R733.3
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