Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《International Journal of Laboratory Medicine》 2006-02
Add to Favorite Get Latest Update

Role of serum κ/λ ratio detection in multiple myeloma diagnosis

LI Hua,ZHAI Tan.Department of Clinical Laboratory,Donghua Hospital of Zhongshan Medical University,Dongguan,Guangdong 523100,China  
Objective To explore the clinical value of the immune rate nephelometry (IRN)in detecting the rate of serum κ and λ,and diagnosing multiple myeloma.Methods Twenty-five cases of multiple myeloma (MM),28 cases of M protein sickness and 120 cases of healthy people were detected for the rate of serum κ/λ by the Immage Protein Machine the results were analyzed.Results 0.8% of healthy people was positive, the positive rate of κ and λ type M protein sickness were 23.1% and 26.7% respectively, the positive rate of κ and λ type multiple myeloma was 92.3% and 100% respectively. Conclusion The method of IRN has high sensitivity and stability in detecting the light chain of serum κ and λ on/with the Immage Protein Machine.The accuracy value of prognosing MM with the rate of serum κ and λ is better.
【CateGory Index】: R733.3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
2 MAO Xiao-Bei1,2,CHEN Xie-Qun1,ZHAI Yong-Ping2,LIANG Rong1,GAO Guang-Xun1,MA Guo-Guang2,YU Ya-Ping2,LI Feng21Department of Hematology,Xijing Hospital,The Fourth Military Medical University,Xi′an 710032,Shaanxi Province,China;2Department of Hematology,Nanjing General Hospital of Nanjing Military Area,Nanjing 210002,Jiangsu Province,China;Measurement of Serum Free Light Chains and Its Clinical Significance in 20 Newly Diagnosed Patients of Multiple Myeloma[J];Journal of Experimental Hematology;2008-04
3 Wan Tang,Zhang Min,Gong Jing-lian,Wang Xiao-gang,Huang Guang-ping(The First Hospital of Nanchang City,Nanchang 330008,China);Clinical value of serum albumin electrophorsis for multiple myeloma[J];Chinese Journal of Health Laboratory Technology;2007-10
Chinese Journal Full-text Database 3 Hits
1 QI Wei-Min;GUO Li(Department of Clinical Laboratories, Tangdu Hospital, Fourth Military Medical University, Xi'an710038);Diagnostic application of quantitation of kappa,lambda light chains and its ratio in patients with multiple myeloma[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1998-04
2 YANG Jun jie 1, ZHANG Guang sen 1, CHEN Xin rui 2, et al (1.Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha 410011, China 2.Clinical Laboratory, The Second Xiangya Hospital, Central South University, Chan;Analysis of monoclonal protein in 72 cases of multiple myeloma[J];Bulletin of Hunan Medical University;2001-02
3 Xu Jiangxia,Liu Ming, Wan Jianxin,Yu Chunshan.Department of Laboratory,Fourth Affiliated Hespital,Jiangxi Medical college,Nanchang 330003;Determination of the immunoglobulin and light chains and its clinical significance in patients with Multiple Myeloma[J];JIANGXI JOURNAL OF MEDICAL LABORATORY SCIENCES;2000-01
Chinese Journal Full-text Database 10 Hits
1 LU Ye-cheng, LIU Li-er, KUANG Yan-ling, et al. (Department of Laboratory Tests, Guangzhou No.8 People′s Hospital, Guangzhou 510060, China);Electro-chemiluminescence Immunoassay for Quantitative Determination of AFP[J];Labeled Immunoassays and Clinical Medicine;2003-04
2 ZOU Han-bing,XU Yi-ping(Renji Hospital,Shanghai Second Medical University,Shanghai 200217,China);Measurement of Spesific IgG to 14 Foods in the Serum of 32 Allergic Patients[J];Labeled Immunoassays and Clinical Medicine;2006-01
3 LIU Ming~1, ZHANG Guo-qing~1, MA Xian-ying~2 (1.Shandong Sports Training and Technology College, Jinan 250014, Shandong China; 2. Shandong Financial College, Jinan 250002, Shandong, China);Research on Oxygen-transport Ability of Swimmers as the Effect of Simulating Altitude Training[J];Journal of Beijing University of Physical Education;2004-06
4 HU Rong~1,KONG Zhao-wei~2,TIAN Ye~3,HU Yang~2(1.Chinese Athletic Association,Beijing,100061,China;2.Beijing University of Physical Education,Beijing 100084,China;3.National Research Institute of Sports Medicine,Beijing 100061,China);Research on Effects of Altitude Training and Simulated HiLo Training on Haematological Changes among Elite Female Runners[J];Journal of Beijing University of Physical Education;2005-11
5 ZHAO Ke-wei (School of Sports & Health,East China Normal University,Shanghai 200062,China);A Summary of the Research Progress in the Effects of Exercise on Interleukin-l,Interleukin-2 and Interleukin-6[J];Journal of Beijing Teachers College of Physical Education;2005-05
6 NIU Min,CHENG Han-fang,PENG Ping,et al.(Municipal Central Hospital of Panzhihua,Panzhihua,Sichuan 617067,China);Influence of physiological saline with human serum as diluent on direct bilirubin detection with vanadate oxidation method[J];Chongqing Medicine;2006-07
7 ;Analysis of humoral immunological features in 2007 M protein positive patients[J];Academic Journal of Second Military Medical University;2004-12
8 WU Shu-mei,LIN Yun,WANG Hui,TANG Ping,QIN Qin,SHEN Qian~* (Department of Laboratory Diagnosis,Changhai Hospital,Second Military Medical University,Shanghai 200433,China);Cause of HBeAg false-negative reaction and it countermeasures[J];Academic Journal of Second Military Medical University;2006-07
9 CHENG Yan-jie1,HAO Cheng-yan2,ZHU Hong1,Wang Xu1,XU Yu-hai1,FAN Cun-lin1,QIN Gui-e1,WU dan1(1.Department of Clinical Laboratory,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;2.Community Health Center,Stone Street of People Square of Xigang Block,Dalian 116011,China);Clinical application of detecting urine protein spectrum and light chain levels in chronic kidney injury[J];Journal of Dalian Medical University;2010-05
10 Liu Hengguo, Luo Nanping, Wang Ruishan, et al. Jinan Military General Hospital, Jinan (250031);Significance of Changes of Serum NSE and CEA Levels in Patients with Pneumonia and Malignant Tumors[J];Journal of Radioimmunology;2005-04
Chinese Journal Full-text Database 6 Hits
1 LIU Wen-yu,MA Jun-long,CHU Gui-xiang,et al.(The General Hospital of Mineral Group of Jixi,Jixi 158100,China);Application of Immunological Detection on Diagnosis of Multiple Myeloma[J];Heilongjiang Medical Journal;2006-11
2 TAN Liming,Li Hua,Qin Hechang,et al.The Second Affili ated H ospital of Jiangxi Medical College,Nanchang330006,China;Detection of serum ceruloplasmin in 17 patients with hepatolenticular dena turalization.[J];Jiangxi Journal of Medical Laboratory Sciences;2003-05
3 SUN DIAN-LIANG,WANG HONG-YI,WANG WEI(Department of Hematology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China);CLINICAL ANALYSIS OF THE EFFICACY OF THALIDOMIDE COMBINED WITH VAD CHEMOTHERAPY FOR MULTIPLE MYELOMA[J];Medical Journal of Qilu;2009-02
4 GUO Cha, HUO Jian, JIANG Hua Department of Hematology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China;Long Distance Vectorette PCR for Detecting Translocation of IgH Gene in Switch Regions of Patients with Multiple Myeloma[J];Journal of Experimental Hematology;2005-03
5 BAI Jie *, SUN Ling, YIN Zong-jian, MA Jun-long, CONG Yu-long. *Clinical Lab of General Hospital of PLA,Beijing 100853, China;Use of serum immunofixation electrophoresis for the diagnosis of renal diseases[J];Chinese Journal of Laboratory Medicine;2003-09
6 Li Shoujing,Li Hongran, Zhao Xiangyin, et al Department of Internal Medicine, Beijing Tong Ren Hospital,Beijing 100730;ON THE DIAGNOSIS OF MULTIPLE MYELOMA AN ANALYSIS OF2547 DOMESTIC CASES[J];CHINESE JOURNAL OF ONCOLOGY;1995-01
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 LIN Xiao-yan,et al.(Xiamen Center of Clinical Laboratory,Zhongshan Hospital,Xiamen,Fujian 361004 China);The clinical significance of Hb n Serum A/G,Hs GRP in multiple myeloma[J];Journal of Qiqihar Medical College;2009-15
2 LIU Xi-ying,SUN Shu-yan,SONG Yuan-yuan.(The First hospital of Jilin Unversity,Jilin Changchun 130021,China);Clinical value of immunofixation electrophoresis,Serum protein electrophoresis,quantitative analysis of in diagnosis of multiple myeloma[J];Chinese Journal of Laboratory Diagnosis;2010-05
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 YuJinxiang,LiCuiluan,LiXia,etal.TheFirstClinicalColege,ChinaMedicalUniversity,Shenyang110001;CirculatingTlymphocytesubsetsandCD38+celsinmultiplemyeloma[J];CHINESE JOURNAL OF HEMATOLOGY;1996-11
2 YangJin-ping*,LiDaqi,WangZhanju,etal.*DepartmentofHematology,AffliatedHospitalofWeifangMedicalColege,Weifang261031;Detectionofinterleukin┐2inpatientswithmultiplemyelomaanditsclinicalimplication[J];CHINESE JOURNAL OF HEMATOLOGY;1996-11
3 Li Shoujing,Li Hongran, Zhao Xiangyin, et al Department of Internal Medicine, Beijing Tong Ren Hospital,Beijing 100730;ON THE DIAGNOSIS OF MULTIPLE MYELOMA AN ANALYSIS OF2547 DOMESTIC CASES[J];CHINESE JOURNAL OF ONCOLOGY;1995-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved