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《International Journal of Laboratory Medicine》 2009-12
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The diagnostic value of lactic acid and adenosine deaminase detection in cerebrospinal fluid of children with meningitis

HUANG Cai-zhi , MO Li-ya , HU Bin, et al. The Children's Hospital of Hu'nan Province, Changsha 410007, China  
Objective To investigate the clinical value of cerebrospinal fluid lactic acid (CSF-LA) and cerehrospinal fluid adenosine deaminase (CSF-ADA) detection in the diagnosis of meningitis in children.Methods Enzyme coloration method and enzymatic rate assay were used to determine the concentration of CSF LA and the activity of CSF-ADA respectively.Results The levels of CSF-LA and CSF-ADA in purulent meningitis group and tubercular meningitis group were significantly higher than those in viral meningitis group and control group (P0.001).CSF LA level in purulent meningitis group was significantly higher than that in tubercular meningitis group (P0.05).The difference of CSF-ADA level was significant between tubercular meningitis group and purulent group (P 0.001),and the positive rate of CSF ADA in tubercular meningitis group was 83.33% (20/24), whereas the CSF-ADA level in purulent meningitis was in normal range.The differences of CSF-LA and CSF-ADA levels between viral group and control group were not significant (P0.05).Conclusion The simultaneous detection of CSF LA and CSF-ADA may be helpful for the clinical diagnosis of meningitis in children.
【CateGory Index】: R446.14;R725.1
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Chinese Journal Full-text Database 1 Hits
1 CHEN Guang-bin, PANG Wei-jun, LU Xian. (Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, Guangdong, P. R. China);The significance of determination of adenosine deaminase in diagnosis of cerebrospinal fluid from infantile tuberculous meningitis patients[J];China Tropical Medicine;2006-06
Chinese Journal Full-text Database 10 Hits
1 FENG Ai-qing et al(Department of Life Science,Luoyang Normal University,Luoyang,Henan 471022);Study on the Determination on Trace Cu in Chinese Herbal Tea by Spectrophotometry with Microwave Digestion[J];Journal of Anhui Agricultural Sciences;2010-21
2 HU Qiu-luan et al(College of Chemistry and Chemical Engineering,Luoyang Normal University,Luoyang,Henan 471022);Determination of Micro-copper in Chinese Herb by Spectrophotometry with Microwave Digestion[J];Journal of Anhui Agricultural Sciences;2010-29
3 LUO Kai-hong,HE Jun-long (Suzhou Municipal Drug Test Center of Jiangsu Province, Jiangsu Suzhou 215002,China);MAIN EFFECT AND TOXICITY OF ZHENLING ORAL FLUID[J];Journal of Anhui Traditional Chinese Medical College;2002-06
4 HE Ling,WANG Jian,HU Jian-peng,GAO Luan(Clinical School of Traditional Chinese Medicine,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230038,China);Effects of Activating Blood and Promoting Diuresis Recipe on Serum Activities of Energy Metabolism Related Enzymes in Rats with Ischemic Brain Edema[J];Journal of Anhui Traditional Chinese Medical College;2012-03
5 YE Zhi-heng,CHU Xiao-hong,JIA Li,ZHAO Guang-bi,WU Bang-qing(Endocrine Laboratory,The First Affiliated Hospital of Anhui Medical University,Hefei Anhui 230022,China);Changes of free triiodothyronine and free thyroxin in high lipid serum pretreated by polyethylene glycol[J];Journal of Bengbu Medical College;2008-02
6 LIU Qun,WANG Min,YANG Yu-ping,HAN Wei-wei,JIN Qi-li(Clinical Laboratory,The Second Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233040,China);Analysis of the causes of false increase in serum MB form creatine kinase activity and its clinical value[J];Journal of Bengbu Medical College;2010-12
7 WANG Wei, YE Yi-xiu, WANG An-sheng, et al. (309 Hospital of PLA, Beijing 100091, China);The Measurement of Collagen Type Ⅳ in Patients with Severe Acute Respiratory Syndrome and Its Clinical Significance[J];Labeled Immunoassays and Clinical Medicine;2003-03
8 YE Yi-xiu,WANG Wei,LI Hong-min,et al. (309 Hospital of PLA,Beijing 100091,China);The Measurement of Superoxide Dismutase in Patients with Severe Acute Respiratory Syndrome and Its Clinical Significance[J];Labeled Immunoassays and Clinical Medicine;2003-03
9 XIONG Chuan-zheng,ZHU Hai-bo,DENG Jian-ping(The Love health Hospital of Huangshi,Huangshi 435000,China);Clinical Significance of Detection of Serum TBA and ALP in Diagnosis of Intrahepatic Cholestasis of Pregnancy[J];Labeled Immunoassays and Clinical Medicine;2009-03
10 WANG Jian-zhu,JIA Xing-wang,DONG Zhen-nan,TIAN Ya-ping(Department of Clinical Biochemistry,PLA General Hospital,Beijing 100853,China);Evaluation of Immunoturbidimetric Assay for Detection of Plasma Concentration of HbA1c[J];Labeled Immunoassays and Clinical Medicine;2011-05
China Proceedings of conference Full-text Database 2 Hits
1 LI Hong,WANG Ke-yue,SUN An-sheng,SHI Xiu-quan,ZHOU Xi-lei.(Department of Preventive Medicine,Zunyi Medical College,Zunyi 563003,China);Study on the Protective Effects of Pre-supplement Zinc on decreasing the Activities of ALP and SOD in Liver and serum of Rat Induced by Cadmium[A];[C];2004
2 Shi Xiuquan Wang Keyue Li Hong et al (Preventive Department of Zunyi Medical College,563003);Study on the Effect of Embryo Damage of Rat Induced by Cadmium[A];[C];2005
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 LIU Yan hua,XUE Cheng yan,YU Hai rong,et al (Department of Function Experiment,Chengde Medical College,Hebei Chengde 067000,China);DETECTION OF LAM-IG AND ADA IN CEREBROSPINAL FLUID FOR DIFFERENTIAL DIAGNOSIS OF TUBERCULOUS MENINGITIS[J];Journal of Chengde Medical College;2001-03
2 Miao Lining,Gu Hua(Department of Nephrology,The Second Clinical Hospital of Norman Bethune University of Medical Sciences,Changchun 130041);Detection of activity of adenosine deaminase in peritoneal dialysis fluid and its clinical significance[J];JILIN MEDICAL JOURNAL;2000-04
3 LIU Xiu-li*,HE Jun-ying, JIN Bian-fen,GONG Zhong,MENG Zhao-hua *Department of Neurology, the 2nd Hospital of Hebei Medical University, Shjiazhuang 050000,China;Dynamic study on activity of adenosine deaminase in cerebrospinal fluid from patients with tuberculous meningitis in adults[J];Clinical Focus;2004-21
4 Cai Long, Li Dejing,Yu Xiaofang. The Red Cross Hospital of Hangzhou 310003, Zhejiang, China;Diagnostic value of cerebrospinal fluid adenosine deaminase activity in tubercular meningitis[J];Clinical Education of General Practice;2004-02
5 MU Fa-guang1,OU-YANG Ying1,CHEN Chang-hui1,ZHANG Jian-bo2 (1.Department of Pediatrics;2.Central Laboratory,Sichuan Provincial People's Hospital,Chengdu 610072,China);Leves of Tumor Necrosis Factor Alpha,Interleukin-1 Beta,Interleukin-6 in Serum and Cerebrospinal Fluid in Children with Intracranial Infection[J];Journal of Applied Clinical Pediatrics;2007-01
6 XUE Cheng yan,LIU Lan fang,LIU Xia,et al. Affiliated Hospital of Chengde Medical College,Chengde 067000;Uniting detection of lipoarabinomannan-IgG and TB-DNA in cerebrospinal fluid for the diagnosis of tuberculous meningitis[J];Buccetin of Chinese Antituberculosis Assoclation;2001-05
7 ZHU Min.Zhejiang combining traditional Chinese Medicine and West Medicine hospital,Hangzhou 310003;Clinical analyses of 62 cases with atypical tuberculosis meningitis[J];Bulletin of Chinese Antituberculosis Association;2003-04
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