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《International Journal of Laboratory Medicine》 2011-01
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Mycroplasma infection and its tendency of drug susceptibility in urogenital tract

Deng Zhaoxiang(Guangdong Frontier Garrison Hospital of Armed Police Force,Shenzhen 518029,Guangdong 518029,P.R.China)  
Objective To know about the urogenital tract infections caused by Mycoplasma in Shenzhen and the sensitivities to the 10 antimicrobials in vitro,to provide guidance for rational clinical treatment.MethodsUreaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) were detected with lath culture sensitivity reagent method for 637 patients with urogenital tract infection and drug susceptibility test results were analyzed for antibiotics.ResultsAmong the 637 samples,317 were positive(49.8%),Among 142 males,56 were positive(39.4%).Among 495 females,261 were positive(52.7%).Females were more apt to be infected(χ2=77.9,P0.01).The positive rate of Uu infection,Mh infection,both Uu and Mh infection was 33.3%,0.9%,15.5%,respectively.The results of drug sensitivity showed that over 83.3% of Mycoplasma were sensitive to josamycin,minocyclin and doxcycline.Ciprofloxacin got the highest drug resistance rate in Uu and both Uu and Mh,all higher than 74.1%.Both roxithromycin and azitromucin had the highest drug resistance in Mh(83.3%).The rate of 47.9% among 317 positive samples had multi-resistance.ConclusionThe infection rate of Mycoplasma in the patient with urogenital tract infection in Shenzhen is high,especially the infection of Uu is usual.Mh,both Uu and Mh in the patient are in a rising tendency.The clinical doctor should rationally choose and use antibiotics according to the drug susceptibility.If drug sensitivity tests is failed to be done,josamycin,doxcycline and minocyclin should be choosed as the main drugs.
【CateGory Index】: R446.5
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