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《International Journal of Laboratory Medicine》 2011-02
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The Early Diagnostic Value of hs-CRP,UmAlb and HbA1c in Diabetic Nephropathy Patients

Li Xin(Department of Laboratory,Huanghe Hospital,Tianjin 300110,China)  
Objective To discuss the value of hs-CRP,UmAlb and HbA1c in early diagnostics of diabetic nephropathy(DN) patients.Methods65 cases of type 2 diabetes mellitus(T2DM) patients were enrolled and divided into two groups according to the excretion rate of UmAlb,one group with early diabetic nephropathy(EDN,35 cases),the other without diabetic nephropathy(NDN,30 cases).30 healthy people were selected as health controls(HC).hsCRP,UmAlb,fasting blood glucose(FBG),triglyceride(TG),total cholesterol(TC),urea nitrogen(BUN),creatinine(Cr),high density lipoprotein(HDL-C),low density lipoprotein(LDL-C) and HbA1c were detected and analyzed.ResultshsCRP,UmAlb and HbA1c concentration of EDN group were significantly higher than NDN and HC group.In 65 cases of T2DM patients,there were positive correlation between hsCRP,HbA1c and UmAlb.ConclusionhsCRP,UmAlb and HbA1c are important indicators of early diagnosis of type 2 diabetic nephropathy patients and have important monitor significance for prevention,treatment and prognosis of diabetic nephropathy patients.
【Key Words】: diabetic nephropathies C-reaction protein hemoglobins early diagnose urea-microalbumin
【CateGory Index】: R587.2
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 OU Wen-hua, CHEN Xiao-yu, SU Xi-kang, WEN Shao-lei (The First People's Hospital of Foshan, Foshan 528000, China);Diagnostic value of urinary mAlb and N-acetyl -β-D-glucosaminidase in patients with early diabetic nephropathy[J];China Medical Herald;2008-35
2 CHEN Yan, ZHAO Min, ZHANG Jia-hong, BA Jing, HAN Yü-shu, ZHANG Li-Xia. Diagnosis Department of the 1 st Affiliated Hospital of China Medical University Shenyang 110001, China;Monitoring diabetes nephropathy by urine examination[J];Chinese Journal of Laboratory Medicine;2003-09
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 LU Jin, JIN Yi,WU Yuan-jian (Department of Laboratory Medicine Suzhou No. 2 People's hospital, Suzhou 215002);Clincal Application of Early Diagnosis of Urinal Microprotein Detection in Diagnosing Diabetic Nephropathy[J];Chinese Journal of Hemorheology;2004-01
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