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《International Journal of Laboratory Medicine》 2011-02
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The Early Diagnostic Value of hs-CRP,UmAlb and HbA1c in Diabetic Nephropathy Patients

Li Xin(Department of Laboratory,Huanghe Hospital,Tianjin 300110,China)  
Objective To discuss the value of hs-CRP,UmAlb and HbA1c in early diagnostics of diabetic nephropathy(DN) patients.Methods65 cases of type 2 diabetes mellitus(T2DM) patients were enrolled and divided into two groups according to the excretion rate of UmAlb,one group with early diabetic nephropathy(EDN,35 cases),the other without diabetic nephropathy(NDN,30 cases).30 healthy people were selected as health controls(HC).hsCRP,UmAlb,fasting blood glucose(FBG),triglyceride(TG),total cholesterol(TC),urea nitrogen(BUN),creatinine(Cr),high density lipoprotein(HDL-C),low density lipoprotein(LDL-C) and HbA1c were detected and analyzed.ResultshsCRP,UmAlb and HbA1c concentration of EDN group were significantly higher than NDN and HC group.In 65 cases of T2DM patients,there were positive correlation between hsCRP,HbA1c and UmAlb.ConclusionhsCRP,UmAlb and HbA1c are important indicators of early diagnosis of type 2 diabetic nephropathy patients and have important monitor significance for prevention,treatment and prognosis of diabetic nephropathy patients.
【CateGory Index】: R587.2
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