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《International Journal of Laboratory Medicine》 2011-08
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Clinical value of combined detection of several serum items in the diagnosis of liver and gallbladder diseases

Li Xirong1,Zeng Jiangtao2,Dong Hui3,Feng Chengjuan1(1.Laboratory;2.Liver Specialist,Subsidiary of Guangzhou University of Traditional Chinese Medicine Hospital,Maoming,Guangdong 525000,China;3.Department of Laboratory Medicine,Guangdong Provincial People′s Hospital Pathology,Guangzhou 510030,China)  
Objective To investigate the clinical value of adenosine deaminase(ADA),α-fucosidase(AFU),alanine aminotransferase(ALT) and total bile acid(TBA)in the diagnosis of liver and gallbladder diseases.Methods 150 cases of patients with liver and gallbladder diseases and 40 cases of healthy controls were enrolld and detected for serum levels of the mentioned items by using SYNCHRON LX-20 automatic biochemical analyzer.Then the deteced results were statistically analyzed.Results The serum levels of the four indicators increased with variant digree in all disease groups.Serum ADA levels of patient groups with acute hepatitis,chronic active hepatitis,chronic persistent hepatitis,and hepatic cirrhosis were significantly different(P0.05).Serum TBA levels of patient groups with acute hepatitis and hepatic cirrhosis were highr than of patients groups with chronic persistent hepatitis and chronic active hepatitis(P0.05).Serum level AFU of patient groups with acute hepatitis,liver cirrhosis and liver cancer increased significantly(P0.05).Conclusion Combined detection of serum items could have certain clinical value in the diagnosis of liver and gall diseases.
【CateGory Index】: R446.1
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