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《International Journal of Laboratory Medicine》 2011-15
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Applicable value of three serology detection methods for the diagnosis of syphilis

Li Aimin,Liu Bin,Cai Feng(Clinical Laboratory Centre,Ruici Hospital,Nantong Jiangsu 226010,China)  
Objective To evaluate the clinical value of ELISA,rapid plasma regain test(RPR) and treponema pallidum particle assay(TPPA) in the detection of syphilis.Methods The serums of 175 syphilitic cases and 120 non-syphilis patients were detected by ELISA、RPR and TPPA.Then,the sensitivity,specificity,false positive rate and false negative rate of different methods were compared.Results The sensitivity and specificity were 74.28% and 78.33% for RPR,100.0% and 96.66% for ELISA,100.0% and 100.0% for TPPA.The sensitivity and specificity of ELISA and TPPA were higher than RPR(P0.05).The false negative rate and the false positive rate of RPR were 25.71% and 21.66%,which were higher than ELISA and TPPA.Conclusion RPR was not suitable for syphilis antibody screening.ELISA could be used for syphilis screening,and TPPA was suitable for confirming positive samples,detected by ELISA.
【CateGory Index】: R759.1
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 ZHOU Xiu-ping1,YANG Chang-shun2,LIU Zhi-jie1,LI Zhen-min1.1.Huaihua Medical College,Hunan 418000,China;2.First People′s Hospital of Huaihua,Hunan 418000,China;Evaluation of three methods for the detection of syphilis[J];Laboratory Medicine and Clinic;2010-17
2 CAO Shu-zheng,WANG Wen-wu,ZHANG Zhen-lu.Department of Laboratory,Asia Heart Hospital,Wuhan 430022,China;Analyses of syphilis assay for the samples in the gray zone[J];The Journal of Practical Medicine;2010-03
3 WANG Lunan, DENG Wei, LI Jinming National Center for Clinical Laboratory, Beijing 100730,China;Clinical evaluation of different serological diagnosis methods of syphilis[J];Chinese Journal of Laboratory Medicine;2002-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Cai Liping1,2,Xu Yong1.(1.Soochow University,Suzhou 215123,China;2.Changshu Entry-Exit Inspection and Quarantine Bureau,Changshu 215500,China);Surveillance on Infectious Diseases among Entry-exit Population at Changshu Port[J];Chinese Journal of Frontier Health and Quarantine;2010-02
2 YANG Li-xin,ZENG Jin-feng,XU Xiao-xuan,et al.Department of Clinical Laboratory,Shenzhen Blood Center,Shenzhen 518035,China;Study on the feasibility of syphilis examination in the blood screening[J];International Journal of Laboratory Medicine;2006-02
3 GU Xing-hui,MA Lan,SHANG Gui-fang,et al. (Shenzhen Blood Center,Shenzhen 518035,China);Retrospective Research on Anti-TP Positive Rate among Shenzhen Blood Donors from 2006 to 2008[J];International Journal of Laboratory Medicine;2010-05
4 He Hui,Zhou Yingchun,Liu Jiduo,Pang Zhiyu,Li Cui,Zhu Hailong(the Department of Clinic Laboratory,the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China);A full automatic chemiluminescence immunoassay instrument applied for detection of treponema pallidum antibody in clinic syphilis[J];International Journal of Laboratory Medicine;2011-13
5 Zhou Meng1,Bi Yankui2Affiliated Ruikang Hospital to Guangxi College of Chinese Medicine,Nanning,Guangxi,China 530001 2006 Grade Postgraduate,Guangxi College of Chinese Medicine,Nanning,Guangxi,China 530001;The Analysis and Strategy of HIV/AIDS Combined Syphilis Infection[J];Journal of Henan University of Chinese Medicine;2009-04
6 Ye Guangrong,Zhang Wei,Huang Xianxiang,Department of Dermatovenereology,the 4th People's Hospital of Panzhihua City,Sichuan Province,P.R.China 617061;Study on the Effect of Different Curative Opportunities on the Prognosis of Pregnant Syphilis[J];Journal of Military Surgeon in Southwest China;2010-06
7 LIU Bing CHEN Hua-gen YANG Dao-qiong Department of Clinical Laboratory,Xindu People's Hospital,Xindu,Sichuan 610500,China;Application for diagnosis of primary syphilis by polymerase chain reaction techniguc[J];Journal of Laboratory Medicine and Clinical Sciences;2004-02
8 OUYANG Ling,XIE Xiu-hua,HUANG Shou-ming,DENG Ai-ling.Department of Clinical Laboratory,Shenzhen Baoan Blood Center,Shenzhen 518101,China;Comparison of four kinds of syphilis testing methods in blood donations[J];Laboratory Medicine and Clinic;2010-04
9 SUN Jun,LIU Mei-hua,YAN Zhong(Zhoukou Hospital of TCM,Zhoukou,Henan 466000,China);Comparison of the two methods on examing the syphilis[J];Laboratory Medicine and Clinic;2011-09
10 Tan Bo Guo Gang Jia Cuiying Wang Linbing Baolatibieke·Silamu Xinjiang international travel healthcare center(Urumqi,830063);Analysis on the surveillance of syphilis results to the pilgrims during 2002 to 2007[J];Port Health Control;2008-05
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Wang Yuying,Zhao Wenbo,Peng Minfeng,et al Chinese Medicine Hospital in Hangzhou,Zhejiang Province(310007);TPPA and RPR Joint Detection of the Experimental Study of Syphilis Antibody[J];Journal of Zhejiang University of Traditional Chinese Medicine;2009-04
2 GU Wei-ming,WANG Xue-min,LE Jia-yu(Shanghai Skin Disease&STD Hospital,Shanghai200050,China);Laboratory diagnosis of early congenital syphilis[J];Journal of Clinical Dermatology;2002-09
3 Tang Quangui;Gu Weining; Zhang Hao et al(Shanghai STD Centre);Comparison of innunoblotting assay wirh hemagglutination test in the detetion of syphilis[J];JOURNAL OF CLINICAL DERMATOLOGY;1995-06
4 Yang Wenlin,Yang Jian,Liu Danrong,Li Zhizhong,Hou Jie (Department of Dermatology, the Second Affiliated Hospital of Guangzhou Medical College, 510260);Serologic change of patients with early syphilisbefore and after therapy[J];JOURNAL OF CLINICAL DERMATOLOGY;1998-05
5 DU Jian - wei, Hainan Provincial Health and Anti - epidemic Station, Haikou 570203. P. R. China.;Analysis of the prevalent trend of syphilis from 1990 to 1999 in Hainan Province[J];China Tropical Medicine;2002-01
6 Jiang Yongjun , Shang Hong, Lu Chunming , Wang Yanan ,et al. The first affiliated hospital, China Medical University, Shenyang, 110001 P. R . China;Survey of HIV, HBV, HCV and syphilis infection among risk groups in Shenyang[J];Journal for China AIDS/STD;2002-01
7 Qian Yihong,Zhang Gang,Gu Zhiying,et al Shanghai Skin Disease & STD Hospital,Shanghai 200050,P R China;Clinical Epidemiological Study of 3,024 Cases with Syphilis[J];Journal for China AIDS/STD;2002-06
8 XIAO Wei,HE Pei,YUAN Jing-er.(Beilun District Center for Disease Control and Prevention,Ningbo 315800,China);EPIDEMIOLOGICAL ANALYSIS OF SEVEN KINDS OF SEXUALLY TRANSMITTED DISEASES IN BEILUN DISTRICT OF NINGBO CITY DURING 1987-2005[J];Modern Preventive Medicine;2007-08
9 YI Yue-ping(Dermatosis Research Institute,Chinese Academy of Medicine and Science,Nanjing 210042,China);Evaluation of serological test for syphilis[J];Practical Journal of Clinical Medicine;2006-02
10 HAN Yu,XU Xiu-mei,ZHANG Yan-ping Tongliao Center for Disease Control and Prevention,Tongliao,lnner Mongolia,028000,China;The Analysis and Compare of the Three Detection Methods of Syphilis Serology[J];Chinese Primary Health Care;2008-02
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