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《International Journal of Laboratory Medicine》 2013-04
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Analysis on HIV infection status of voluntary blood donors in Shenzhen

Gu Xinghui,Xiong Wen,Zeng Xuezhen,Chen Yunlong,Wang Songxing,Liu Heng,Wu Lingfeng(Shenzhen Blood Center,Shenzhen,Guangdong 518035,China)  
Objective To explore the human immunodeficiency virus(HIV) infection status among blood donors in Shenzhen.Methods With the ELISA,the specimens of voluntary blood donors collected between 2007 and 2011 were tested respectively for anti-HIV1/2 antibody and p24 antigen.The positive specimens were sent to Shenzhen CDC for further confirmation by WB assay.Results From 2007 to 2011,302 422 donors were tested,69 were confirmed as HIV positive.The positive rate of HIV has undergone a yearly increase(χ2=25.505,P0.005).There was significant gender-based differences of HIV infection among voluntary blood donors(χ2=20.471,P0.005).Among the HIV infectors,pure HIV infection accounts for a majority of 74%,followed by the concurrent Treponema pallidum infection(25%) and HCV infection(1%).Conclusion Pre-donation consultation and screening should be strengthened,testing time of window period should be shortened and reagents with high sensitivity should be used to ensure the blood transfusion safety.
【CateGory Index】: R181.3
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